Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Oct 19, 2023; 13(10): 732-742
Published online Oct 19, 2023. doi: 10.5498/wjp.v13.i10.732
Sleep disturbances are associated with anxiety, depression, and decreased quality of life in patients with coronary heart disease
Da Zheng, Rui-Juan Tan, Wei Liu, Peng-Cheng Song, Feng-De Li
Da Zheng, Feng-De Li, Department of Cardiovascular Medicine, Hengshui People’s Hospital, Hengshui 053000, Hebei Province, China
Rui-Juan Tan, Department of Pharmacy, Hengshui People’s Hospital, Hengshui 053000, Hebei Province, China
Wei Liu, Department of Psychiatry, Hengshui People’s Hospital, Hengshui 053000, Hebei Province, China
Peng-Cheng Song, Department of Traditional Chinese Medicine, Hengshui People’s Hospital, Hengshui 053000, Hebei Province, China
Author contributions: Zheng D initiated the project and designed the experiment; Tan RJ conducted the clinical data collection; Liu W performed postoperative follow-up and recorded the data; Song PC conducted a number of collation and statistical analyses; Li FD wrote the original manuscript and revised the paper; All authors read and approved the final manuscript.
Supported by Scientific Research Program on Chinese Medicine, No. 2023460.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the Hengshui People’s Hospital.
Informed consent statement: As the study used anonymous and pre-existing data, the requirement for the informed consent from patients was waived.
Conflict-of-interest statement: The authors have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Feng-De Li, Doctor, Department of Cardiovascular Medicine, Hengshui People’s Hospital, No. 180 Renmin Road, Taocheng District, Hengshui 053000, Hebei Province, China. lifengdehssrmyy@163.com
Received: June 30, 2023
Peer-review started: June 30, 2023
First decision: July 18, 2023
Revised: August 8, 2023
Accepted: August 25, 2023
Article in press: August 25, 2023
Published online: October 19, 2023
Processing time: 103 Days and 19.6 Hours
Abstract
BACKGROUND

Studies have shown that sleep disorders are closely related to anxiety and depression, and the quality of life (QoL) of patients with sleep disorders is generally poor.

AIM

To examine the occurrence of sleep disorders in people with coronary heart disease (CHD) and their relationships with QoL, depression, and anxiety.

METHODS

As per the sleep condition, 240 CHD individuals were separated into two groups: non-sleep disorder group (n = 128) and sleep disorder group (n = 112). The self-rating anxiety scale (SAS), self-rating depression scale (SDS), and World Health Organization criteria for the Quality of Life Brief scale (WHOQOL-BREF) scores of the two groups were compared. Logistic regression method was used to analyze the independent risk factors of CHD patients with sleep disorders. Multivariate logistic regression analysis was employed to develop the risk prediction model. The association among the Pittsburgh Sleep Quality Index, SAS, and SDS was examined using Spearman’s correlation analysis.

RESULTS

The incidence of sleep disorder was 46.67% in 240 patients. The scores of SAS and SDS in the sleep disorder group were higher than those in the non-sleep disorder group, and the WHOQOL-BREF scores were lower than those in the non-sleep disorder group (P < 0.05). The risk prediction model of sleep disturbances in CHD patients was constructed using the outcomes of multivariate logistic regression analysis, P = 1/[1 + e (-2.160 + 0.989 × (female) + 0.001 × (new rural cooperative medical insurance) + 2.219 × (anxiety) + 2.157 × depression)]. The results of a Spearman’s correlation study revealed that sleep quality was strongly adversely connected with the physiological field, psychological field, and social relation scores in QoL, and was considerably positively correlated with SAS and SDS (P < 0.05).

CONCLUSION

A multivariate logistic regression model can better predict the occurrence of sleep disorders in CHD patients. Sleep disorders in CHD patients are significantly correlated with QoL, depression, and anxiety.

Keywords: Coronary heart disease; Sleep disorder; Quality of life; Depression; Anxiety

Core Tip: Sleep disorder is a common clinical problem, and the correlation between sleep disorder and anxiety and depression has been widely discussed in clinical practice. This study explored the problem of sleep disorder in patients with coronary heart disease (CHD) and its correlation with anxiety, depression, and quality of life (QoL). The results showed that the incidence of sleep disorder is higher in patients with CHD, and is positively correlated with anxiety and depression, and negatively correlated with QoL.