Sodium selenite may be not the optimal speciation as an effective therapy for arsenic-induced anxiety-/depression-like behavior

doi:10.5498/wjp.v12.i9.1255

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 12, Issue 9

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3858)

All Articles published online

The chart showing PDF series, WORD series, HTML series.

Item

Count

PDF

220

WORD

HTML

1631

Sum=1918

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

563

Download

1378

Sum=1941

Sep 19, 2022 (publication date) through Mar 3, 2026

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Psychiatry

ISSN

2220-3206

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Letter to the Editor

World J Psychiatry. Sep 19, 2022; 12(9): 1255-1257
Published online Sep 19, 2022. doi: 10.5498/wjp.v12.i9.1255

Sodium selenite may be not the optimal speciation as an effective therapy for arsenic-induced anxiety-/depression-like behavior

Xiao-Hua Ren, Xiao-Xuan Wang, Lian-Ping He

Xiao-Hua Ren, Xiao-Xuan Wang, Lian-Ping He, School of Medicine, Taizhou University, Taizhou 318000, Zhejiang Province, China

Author contributions: Ren XH and He LP contributed to the conception of research; Ren XH and Wang XX wrote the letter; Wang XX and He LP contributed to the revision of the letter; all authors approved the final manuscript for submission.

Supported by Curriculum Reform Project of Taizhou University in 2021, No. xkg2021087.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Lian-Ping He, PhD, Teacher, School of Medicine, Taizhou University, No. 1139 Shifu Avenue, Jiaojiang District, Taizhou 318000, Zhejiang Province, China. lianpinghe@tzc.edu.cn

Received: March 3, 2022
Peer-review started: March 3, 2022
First decision: April 18, 2022
Revised: April 20, 2022
Accepted: August 26, 2022
Article in press: August 26, 2022
Published online: September 19, 2022
Processing time: 201 Days and 6.3 Hours

Abstract

Major depressive disorder is a serious and prevalent neuropsychiatric disorder, affecting more than 350 million people worldwide. Here, sodium selenite (SS) was selected as the selenite supplement to improve the behavior in a mouse model of depression induced by As. SS may be not the optimal speciation for selenite supplementation and the source of the SS used in the study was not disclosed. There are many mouse models of depression and anxiety; however, in the current study, a classical mouse model of depression was not used. Thus, several questions still need to be further discussed. Taken together, the results indicate that SS may be not the optimal speciation as an effective therapy for As-induced anxiety-/depression-like behavior.

Keywords: Depression; Arsenic; Major depressive disorder; Sodium selenite; Optimal speciation

Core Tip: Sodium selenite (SS) may be not the optimal speciation for selenite supplementation and the source of the SS used in the study was not disclosed. There are many mouse models of depression and anxiety; however, in the current study, a classical mouse model of depression was not used.