Systematic Reviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Nov 19, 2021; 11(11): 1129-1146
Published online Nov 19, 2021. doi: 10.5498/wjp.v11.i11.1129
New-onset depression after hip fracture surgery among older patients: Effects on associated clinical outcomes and what can we do?
Hao-Cheng Qin, Zhi-Wen Luo, Heng-Yi Chou, Yu-Lian Zhu
Hao-Cheng Qin, Yu-Lian Zhu, Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
Zhi-Wen Luo, Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
Heng-Yi Chou, Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China
Author contributions: Qin HC and Luo ZW conducted the original search and wrote the first draft of the paper; Qin HC, Luo ZW ,and Chou HY screened the selected articles and contributed to subsequent drafts of the manuscript; Zhu YL conceived the idea for the study and provided suggestions; Qin HC and Luo ZW made equal contributions to the work.
Conflict-of-interest statement: The authors admitted that there is no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Lian Zhu, MD, PhD, Doctor, Professor, Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, No. 12 Wulumuqi road, Jing’an District, Shanghai 200040, China. zyljully@163.com
Received: May 17, 2021
Peer-review started: May 17, 2021
First decision: June 23, 2021
Revised: June 25, 2021
Accepted: August 23, 2021
Article in press: August 23, 2021
Published online: November 19, 2021
Processing time: 183 Days and 23 Hours
Abstract
BACKGROUND

Hip fracture in the elderly is a worldwide medical problem. New-onset depression after hip fracture has also received attention because of its increasing incidence and negative impact on recovery.

AIM

To provide a synthesis of the literature addressing two very important questions arising from postoperative hip fracture depression (PHFD) research: the risk factors and associated clinical outcomes of PHFD, and the optimal options for intervention in PHFD.

METHODS

We searched the PubMed, Web of Science, EMBASE, and PsycINFO databases for English papers published from 2000 to 2021.

RESULTS

Our results showed that PHFD may result in poor clinical outcomes, such as poor physical function and more medical support. In addition, the risk factors for PHFD were summarized, which made it possible to assess patients preoperatively. Moreover, our work preliminarily suggested that comprehensive care may be the optimal treatment option for PHFDs, while interdisciplinary intervention can also be clinically useful.

CONCLUSION

We suggest that clinicians should assess risk factors for PHFDs preoperatively, and future research should further validate current treatment methods in more countries and regions and explore more advanced solutions.

Keywords: Depression; Hip fracture; New onset; Risk factors; Treatments; Clinical outcomes

Core Tip: Although postoperative hip fracture depression (PHFD) has terrible effects on older patients, the risk factors, associated clinical outcomes, and treatments have not been systematically summarized. The comprehensive identification of risk factors is clinically useful in preoperative assessment and early prevention of PHFD. In addition, the summarized treatment options for PHFDs can suggest what circumstances treatment works best, providing a credible guide for effective management for clinicians.