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For: Onaolapo AY, Onaolapo OJ. Glutamate and depression: Reflecting a deepening knowledge of the gut and brain effects of a ubiquitous molecule. World J Psychiatr 2021; 11(7): 297-315 [PMID: 34327123 DOI: 10.5498/wjp.v11.i7.297]
URL: https://www.wjgnet.com/2220-3206/full/v11/i7/297.htm
Number Citing Articles
1
André Ribeiro Buinho, Francisca Ribeirinho Soares, João Paulo Rema. Exploring Therapeutic Potential: A Comprehensive Review of Novel Treatment Targets in Psychotic DepressionCurrent Treatment Options in Psychiatry 2024; 11(3) doi: 10.1007/s40501-024-00329-6
2
Benjamin F. Gruenbaum, Alexander Zlotnik, Anna Oleshko, Frederic Matalon, Honore N. Shiyntum, Amit Frenkel, Matthew Boyko. The Relationship between Post-Traumatic Stress Disorder Due to Brain Injury and Glutamate Intake: A Systematic ReviewNutrients 2024; 16(6) doi: 10.3390/nu16060901
3
Hai-Ha Nguyen, Jintanaporn Wattanathorn, Wipawee Thukham-Mee, Supaporn Muchimapura, Pongsatorn Paholpak. Development of a Guava Jelly Drink with Potential Antioxidant, Anti-Inflammation, Neurotransmitter, and Gut Microbiota BenefitsFoods 2025; 14(13) doi: 10.3390/foods14132401
4
Douglas F. Watt. The separation distress hypothesis of depression – an update and systematic reviewNeuropsychoanalysis 2023; 25(2) doi: 10.1080/15294145.2023.2240340
5
Shih‐Hsien Lin, Po See Chen, Shih‐Ming Huang, Yen Kuang Yang. Glutamate concentrations related to depression and mania symptoms in patients with Graves' disease: A 1H‐magnetic resonance spectroscopy studyThe Kaohsiung Journal of Medical Sciences 2024; 40(8) doi: 10.1002/kjm2.12854
6
Xiangyan Zhou, Sixing Wang, Xiaohui Wang, Xinran Chen, Pei Zhou, Kai Ma, Peng Zhang. Mechanisms of the effect of gut microbes on depression through the microbiota-gut-brain axisFrontiers in Nutrition 2025; 12 doi: 10.3389/fnut.2025.1634548
7
Annisa Citra Herrastri Hertanto, Ancah Caesarina Novi Marchianti, Muhammad Hasan. Hubungan Antara Pola Makan dan Aktivitas Fisik Terhadap Tingkat Depresi di Masa Pandemi Pada Pelajar SMAN 1 Manyar Gresik, IndonesiaAmerta Nutrition 2023; 7(2) doi: 10.20473/amnt.v7i2.2023.283-294
8
Sebastian Reyes-Lizaola, Ulises Luna-Zarate, Hiram Tendilla-Beltrán, Julio César Morales-Medina, Gonzalo Flores. Structural and biochemical alterations in dendritic spines as key mechanisms for severe mental illnessesProgress in Neuro-Psychopharmacology and Biological Psychiatry 2024; 129 doi: 10.1016/j.pnpbp.2023.110876
9
Stephanie S. Römer, Theresa A. Larkin, Vida Bliokas, Asmahan Elgellaie, Susan J. Thomas. The association of plasma glutamate with food addiction in individuals with major depressive disorderAppetite 2026; 216 doi: 10.1016/j.appet.2025.108317
10
Samantha Schildroth, Birgit Claus Henn, Anissa I. Vines, Ruth J. Geller, Sharonda M. Lovett, Chad M. Coleman, Traci N. Bethea, Julianne Cook Botelho, Antonia M. Calafat, Chad Milando, Donna D. Baird, Ganesa Wegienka, Lauren A. Wise. Per- and polyfluoroalkyl substances (PFAS), perceived stress, and depressive symptoms in a prospective cohort study of black womenScience of The Total Environment 2024; 929 doi: 10.1016/j.scitotenv.2024.172445
11
Sepideh Hajivalizadeh, Kimia Farahmand, Kimia Kazemzadeh, Ghazaleh Hajivalizadeh, Ahmad Shamabadi. Pharmacotherapeutic Management of Depression in Patients With Cancer: A Review of Mechanistic and Clinical EvidenceCancer Reports 2026; 9(5) doi: 10.1002/cnr2.70587
12
Anil Kumar Rana, Babita Bhatt, Chitralekha Gusain, Surya Narayan Biswal, Debashree Das, Mohit Kumar. Neuroimmunometabolism: how metabolism orchestrates immune response in healthy and diseased brainAmerican Journal of Physiology-Endocrinology and Metabolism 2025; 328(2) doi: 10.1152/ajpendo.00331.2024
13
Hua Fu, Yang Liu. Complex gut–brain interactions underlying inflammatory bowel disease-related depression have translational implications in regenerative medicine: a narrative reviewRegenerative Medicine Reports 2024; 1(1) doi: 10.4103/REGENMED.REGENMED-D-24-00006
14
Amy A. Maury, Kathleen F. Holton. Biomarkers Associated with Depression Improvement in Veterans with Gulf War Illness Using the Low-Glutamate DietNutrients 2024; 16(14) doi: 10.3390/nu16142255
15
Aleksandra Szopa, Karolina Bogatko, Anna Serefko, Mariola Herbet, Marta Ostrowska-Leśko, Andrzej Wróbel, Maria Radziwoń-Zaleska, Jarosław Dudka, Piotr Wlaź, Ewa Poleszak. Antidepressant effects of selective adenosine receptor antagonists targeting the A1 and A2A receptors administered jointly with NMDA receptor ligands: behavioral, biochemical and molecular investigations in micePharmacological Reports 2024; 76(5) doi: 10.1007/s43440-024-00627-z
16
Huakang Li, Jing Wang, Yuanzhen Mi, Cuicui Gong, Ziliang Wu, Pengxuan Gu, Wenxi Zhou, Bing Lin, Ke Xu, Jinyi Lang. Causal effects of gut microbiota and blood metabolites on subtypes of perinatal depression classified based on depressive symptom trajectories: a mendelian randomization studyNutrition & Metabolism 2026; 23(1) doi: 10.1186/s12986-026-01111-6
17
Zahra Bashir, Luisa W. Hugerth, Maria Christine Krog, Stefanie Prast-Nielsen, Gabriella Edfeldt, Fredrik Boulund, Simon Rønnow Schacht, Inge Tetens, Lars Engstrand, Ina Schuppe-Koistinen, Emma Fransson, Henriette Svarre Nielsen. Investigations of microbiota composition and neuroactive pathways in association with symptoms of stress and depression in a cohort of healthy womenFrontiers in Cellular and Infection Microbiology 2024; 14 doi: 10.3389/fcimb.2024.1324794
18
Adejoke Y. Onaolapo, Folusho O. Ojo, Anthony T. Olofinnade, Joshua Falade, Ismail A. Lawal, Olakunle J. Onaolapo. Microbiome-Based Therapies in Parkinson’s Disease: Can Tuning the Microbiota Become a Viable Therapeutic Strategy?CNS & Neurological Disorders - Drug Targets 2023; 22(9) doi: 10.2174/1871527321666220903114559
19
Yali Weng, Yu Zhang, Yinhan Li, Xinpei Lin, Zhenkun Guo, Hong Hu, Wenya Shao, Guangxia Yu, Fuli Zheng, Ping Cai, Huangyuan Li, Siying Wu. Single-cell RNA-sequencing of cellular heterogeneity and pathogenic mechanisms in paraquat-induced Parkinson's disease with depressionEcotoxicology and Environmental Safety 2024; 273 doi: 10.1016/j.ecoenv.2024.116169
20
Lenin Pavón, Danelia Mendieta-Cabrera, Gilberto Pérez-Sánchez, Luis Enrique Becerril-Villanueva, Samantha Alvarez-Herrera, Luis Vallejo-Castillo, Lissette Haydee García-Mena, José Luis Maldonado-García. PsychoNeuroImmunologyIntegrated Science 2024; 31 doi: 10.1007/978-3-031-72079-6_6
21
Dania Akbar, Taeho Greg Rhee, Felicia Ceban, Roger Ho, Kayla M. Teopiz, Bing Cao, Mehala Subramaniapillai, Angela T. H. Kwan, Joshua D. Rosenblat, Roger S. McIntyre. Dextromethorphan-Bupropion for the Treatment of Depression: A Systematic Review of Efficacy and Safety in Clinical TrialsCNS Drugs 2023; 37(10) doi: 10.1007/s40263-023-01032-5
22
José Luis Maldonado-García, Lissette Haydee García-Mena, Danelia Mendieta-Cabrera, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, Samantha Alvarez-Herrera, Toni Homberg, Luis Vallejo-Castillo, Sonia Mayra Pérez-Tapia, Martha C. Moreno-Lafont, Daniel Ortuño-Sahagún, Lenin Pavón. Use of Extracellular Monomeric Ubiquitin as a Therapeutic Option for Major Depressive DisorderPharmaceuticals 2024; 17(7) doi: 10.3390/ph17070841
23
Yara S. Abdelkawy, Mona Elharoun, Eman Sheta, Ihab Talat Abdel-Raheem, Hisham A. Nematalla. Liraglutide and Naringenin relieve depressive symptoms in mice by enhancing Neurogenesis and reducing inflammationEuropean Journal of Pharmacology 2024; 971 doi: 10.1016/j.ejphar.2024.176525
24
O. K. Savushkina, I. S. Boksha, M. A. Omelchenko, E. B. Tereshkina, T. A. Prokhorova, E. A. Vorobyeva, G. Sh. Burbaeva. Correlations between biochemical and clinical parameters in patients at risk for schizophrenia spectrum disordersVestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) 2023; (3) doi: 10.33920/med-01-2303-06
25
O.K. Savushkina, I.S. Boksha, M.A. Omel’chenko, E.B. Tereshkina, T.A. Prokhorova, E.A. Vorobieva, G.Sh. Burbaeva. Activity of enzymes of glutamate, energy and glutathione metabolism in the first juvenile depression with attenuated symptoms of schizophreniaZhurnal nevrologii i psikhiatrii im. S.S. Korsakova 2022; 122(8) doi: 10.17116/jnevro2022122081136
26
Benjamin F. Gruenbaum, Kiran S. Merchant, Alexander Zlotnik, Matthew Boyko. Gut Microbiome Modulation of Glutamate Dynamics: Implications for Brain Health and NeurotoxicityNutrients 2024; 16(24) doi: 10.3390/nu16244405
27
Matthew Boyko, Benjamin F. Gruenbaum, Anna Oleshko, Igor Merzlikin, Alexander Zlotnik. Diet’s Impact on Post-Traumatic Brain Injury Depression: Exploring Neurodegeneration, Chronic Blood–Brain Barrier Destruction, and Glutamate Neurotoxicity MechanismsNutrients 2023; 15(21) doi: 10.3390/nu15214681
28
Mirsol Choi, Xena Wang, Mohit Singh, Jeremy Weleff. Serotonin Syndrome Masquerading as Alcohol Withdrawal: A Case ReportJournal of Addictive Diseases 2026; 44(3) doi: 10.1080/10550887.2025.2545649
29
Benjamin Fredrick Gruenbaum, Alexander Zlotnik, Amit Frenkel, Ilya Fleidervish, Matthew Boyko. Glutamate Efflux across the Blood–Brain Barrier: New Perspectives on the Relationship between Depression and the Glutamatergic SystemMetabolites 2022; 12(5) doi: 10.3390/metabo12050459
30
Simona Mattova, Patrik Simko, Elena Colzi, Erika Stammova, Nicol Urbanska, Maria Grigoroiu-Serbanescu, Elisabetta Coppi, Terezia Kiskova-Simkova. ATP and major affective disorders: the involvement of P2X receptors in pathophysiologyPurinergic Signalling 2026; 22(2) doi: 10.1007/s11302-026-10147-5
31
Cyrus Su Hui Ho, Gabrielle Wann Nii Tay, Hai Ning Wee, Jianhong Ching. The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression SeverityInternational Journal of Molecular Sciences 2023; 24(3) doi: 10.3390/ijms24032231
32
Mengjing Chen, Qiuju Lyu, Lina Huang, Yeliang Lou, Lingfeng Wang. Gut–brain axis and depression: focus on the amino acid and short-chain fatty acid metabolismBehavioural Pharmacology 2025; 36(7) doi: 10.1097/FBP.0000000000000851
33
Amjad Mhanna, Nafiza Martini, Ghefar Hmaydoosh, George Hamwi, Mulham Jarjanazi, Ghaith Zaifah, Reem Kazzazo, Aya Haji Mohamad, Zuheir Alshehabi. The correlation between gut microbiota and both neurotransmitters and mental disorders: A narrative reviewMedicine 2024; 103(5) doi: 10.1097/MD.0000000000037114
34
Essia Hamdi, Slah Hidouri, Marwa Kechnebbou, Salem Amara. Ascorbic acid and glutamate as therapeutics for oxidative stress and behavioral dysfunction in rats exposed to zinc nanoparticlesToxicology and Environmental Health Sciences 2025; 17(1) doi: 10.1007/s13530-024-00246-4
35
Evgenii Gusev, Alexey Sarapultsev. Interplay of G-proteins and Serotonin in the Neuroimmunoinflammatory Model of Chronic Stress and Depression: A Narrative ReviewCurrent Pharmaceutical Design 2024; 30(3) doi: 10.2174/0113816128285578231218102020
36
Gauri Pathak, Aryaa Nigade, Kuttiappan Anitha, Shvetank Bhatt. Current drug targets for the treatment of depressionBrain Disorders 2025; 19 doi: 10.1016/j.dscb.2025.100270
37
Xiaoling Zeng, Xuan Yin, Kaiyu Cui, Wenqing Xu, Xiang Li, Wei Zhang, Wei Li, Shifen Xu. Effect of electroacupuncture on metabolic alterations in the hippocampus and dorsal raphe nucleus of Wistar Kyoto ratsBrain Research 2025; 1850 doi: 10.1016/j.brainres.2024.149409
38
苗佳 余. Changes in Psychological Status of Diabetic Patients after COVID-19 Infection and Its Influencing FactorsAdvances in Clinical Medicine 2024; 14(05) doi: 10.12677/acm.2024.1451594
39
Thanasis Mitsis, Eleni Papakonstantinou, Dimitrios Vlachakis. Biological mechanisms underlying depression, epigenetics and their interplay (Review)International Journal of Epigenetics 2023; 3(1) doi: 10.3892/ije.2023.17
40
Muthukumaran Thulasingam, Chitra Vellapandian. Exploring New Frontiers in Pharmacological Treatment of Depression: A Review on Recent AdvancesCurrent Medicinal Chemistry 2026; 33(6) doi: 10.2174/0109298673342524250109181220
41
Sofia Sakopoulos, McWelling Todman. The Effects of Psychotherapy on Single and Repeated Ketamine Infusion(s) Therapy for Treatment-Resistant Depression: The Convergence of Molecular and Psychological TreatmentInternational Journal of Molecular Sciences 2025; 26(14) doi: 10.3390/ijms26146673
42
Pietro Sarasso, Martina Billeci, Irene Ronga, Fabiola Raffone, Vassilis Martiadis, Gilberto Di Petta. Disembodiment and Affective Resonances in Esketamine Treatment of Depersonalized Depression Subtype: Two Case StudiesPsychopathology 2024;  doi: 10.1159/000539714
43
Mario Gennaro Mazza, Mariagrazia Palladini, Sara Poletti, Francesco Benedetti. Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological TreatmentCNS Drugs 2022; 36(7) doi: 10.1007/s40263-022-00931-3
44
Anshula Mehra, Jaanvi Khanna, Gurpreet Singh, Vridhi Sachdeva, Neena Bedi. A Comprehensive Review on Major Depressive Disorder: Exploring Etiology, Pathogenesis and Clinical ApproachesCurrent Behavioral Neuroscience Reports 2025; 12(1) doi: 10.1007/s40473-025-00308-y
45
Isabela Heroiu, Gia Han Le, Maria-Christina Sioufi, Christine E. Dri, Yang Jing Zheng, Sabrina Wong, Roger S. McIntyre. Ketamine for the Treatment of Obsessive-Compulsive Disorder (OCD): A Systematic Review on Efficacy and TolerabilityClinical Neuropharmacology 2026;  doi: 10.1097/WNF.0000000000000692
46
Tobias Walbert, Edward K Avila, Florien W Boele, Caroline Hertler, Christine Lu-Emerson, Pim B van der Meer, Katherine B Peters, Alasdair G Rooney, Jessica W Templer, Johan A F Koekkoek. Symptom management in isocitrate dehydrogenase mutant gliomaNeuro-Oncology Practice 2025; 12(Supplement_1) doi: 10.1093/nop/npae088
47
Essia Hamdi, Slah Hidouri, Ana-Belén Muniz-Gonzalez, Alberto Marcos Bermejo, César Venero, Salem Amara, Ahmed Landoulsi. The role of glutamic acid-modified silica nanoparticles in promoting brain healthAdvances in Redox Research 2024; 10 doi: 10.1016/j.arres.2024.100095
48
Olga V. Averina, Elena U. Poluektova, Yana A. Zorkina, Alexey S. Kovtun, Valery N. Danilenko. Human Gut Microbiota for Diagnosis and Treatment of DepressionInternational Journal of Molecular Sciences 2024; 25(11) doi: 10.3390/ijms25115782
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Linsun Lin, Ziyi Guo, Zhuoyu Ren, Yanchen Feng, Peigang Fang, Tao Wang, Min Chen. Bibliometric insights into astrocytic roles in depression and treatmentFrontiers in Cellular Neuroscience 2025; 18 doi: 10.3389/fncel.2024.1521398
50
Mia Y. Roberts, Lisa A. Briand. Sex differences in AMPA receptor trafficking proteinsBiology of Sex Differences 2026; 17(1) doi: 10.1186/s13293-026-00849-1
51
Sun-Young Kim, So-Youn Woo, Hyung-Lae Kim, Yoosoo Chang, Seungho Ryu, Han-Na Kim. A shotgun metagenomic study identified short-chain fatty acid-producing species and their functions in the gut microbiome of adults with depressive symptoms: Large-scale shotgun sequencing data of the gut microbiota using a cross-sectional designJournal of Affective Disorders 2025; 376 doi: 10.1016/j.jad.2025.01.149
52
Shuhao Chen, Baoyuan Zhu, Xiaodan Lu, Yuanyuan Huang, Shuhong Wang, Wei Wang, Guanchu Chen, Xuecheng Wu, Jiayi Zhou, Fengchun Wu, Kai Wu. Integrative multi-kingdom gut microbiome analysis uncovers clinical signatures of major depressive disorderJournal of Affective Disorders 2026; 408 doi: 10.1016/j.jad.2026.121858
53
Teng Teng, Fang Huang, Ming Xu, Xuemei Li, Lige Zhang, Bangmin Yin, Yuping Cai, Fei Chen, Luman Zhang, Jushuang Zhang, Aoyi Geng, Chengzhi Chen, Xiaofei Yu, Jing Sui, Zheng-Jiang Zhu, Kai Guo, Chenhong Zhang, Xinyu Zhou. Microbiota alterations leading to amino acid deficiency contribute to depression in children and adolescentsMicrobiome 2025; 13(1) doi: 10.1186/s40168-025-02122-w
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Shu Wang, Yu-Guang Guan, Yan-Hua Zhu, Min-Zhong Wang. Role of high mobility group box protein 1 in depression: A mechanistic and therapeutic perspectiveWorld Journal of Psychiatry 2022; 12(6): 779-786 doi: 10.5498/wjp.v12.i6.779
55
Jiao Li, Chao Zhang, Yao Meng, Siqi Yang, Jie Xia, Huafu Chen, Wei Liao, Laura D. Lewis. Morphometric brain organization across the human lifespan reveals increased dispersion linked to cognitive performancePLOS Biology 2024; 22(6) doi: 10.1371/journal.pbio.3002647
56
Adejoke Y. Onaolapo, Olakunle J. Onaolapo. Natural Molecules in Neuroprotection and Neurotoxicity2024;  doi: 10.1016/B978-0-443-23763-8.00026-9
57
Amir Saeed, Talal Alharazi, Khalid Alshaghdali, Raja Rezgui, Ibtihag Elnaem, Bunder Albdullah T. Alreshidi, Munazzah Tasleem, Mohd Saeed, Rekha Khandia. Targeting GluR3 in Depression and Alzheimer’s Disease: Novel Compounds and Therapeutic ProspectsJournal of Alzheimer's Disease 2024; 97(3) doi: 10.3233/JAD-230821
58
Gita Kholghi, Shirin Arjmandi-Rad, Mohammad-Reza Zarrindast, Salar Vaseghi. St. Johnʼs wort (Hypericum perforatum) and depression: what happens to the neurotransmitter systems?Naunyn-Schmiedeberg's Archives of Pharmacology 2022; 395(6) doi: 10.1007/s00210-022-02229-z
59
Meijia Shan, Jingyue Zhang, Fuqin Yang, Fengchuan Cao, Yaru Yang, Wen Li, Limei Wang. Glabridin Improves Depression-Like Behaviors in Mice by Modulating Neuroinflammation via MAPK/NF-κB Signaling PathwayNeurochemical Research 2025; 50(6) doi: 10.1007/s11064-025-04593-7
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Catalina Torres Soler, Sofia H. Kanders, Mattias Rehn, Susanne Olofsdotter, Cecilia Åslund, Kent W. Nilsson. A Three-Way Interaction of Sex, PER2 rs56013859 Polymorphism, and Family Maltreatment in Depressive Symptoms in AdolescentsGenes 2023; 14(9) doi: 10.3390/genes14091723