Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Exp Med. Mar 20, 2026; 16(1): 111034
Published online Mar 20, 2026. doi: 10.5493/wjem.v16.i1.111034
Published online Mar 20, 2026. doi: 10.5493/wjem.v16.i1.111034
Acute childhood leukemia and ophthalmic manifestations: An observational study from Eastern India
Sucheta Parija, Shanmugasundaram Palanisamy, Department of Ophthalmology, All India Institute of Medical Sciences, Bhubaneshwar 751019, Odisha, India
Co-corresponding authors: Sucheta Parija and Shanmugasundaram Palanisamy.
Author contributions: Parija S contributed to concept, analysis, writing and editing of article; Palanisamy S contributed to data collection, Statistical analysis, proofreading and editing; Parija S and Palanisamy S have played important and indispensable roles in the manuscript preparation as the co-corresponding authors.
Institutional review board statement: Ethical approval was obtained from the All India Institute of Medical Sciences.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement- checklist of items.
Data sharing statement: No data shared.
Corresponding author: Sucheta Parija, Professor, Department of Ophthalmology, All India Institute of Medical Sciences, Sujia, Patrapada, Bhubaneshwar 751019, Odisha, India.
Received: June 24, 2025
Revised: August 14, 2025
Accepted: January 6, 2026
Published online: March 20, 2026
Processing time: 266 Days and 19.9 Hours
Revised: August 14, 2025
Accepted: January 6, 2026
Published online: March 20, 2026
Processing time: 266 Days and 19.9 Hours
Core Tip
Core Tip: This study was undertaken to analyze the ocular features of cases of acute leukemia in children. Most of the cases are asymptomatic at presentation and can manifest with vision-threatening features in the form of vitreous hemorrhage and subhyaloid hemorrhage in the posterior pole, which needs immediate treatment. Hence, periodic ocular examinations are needed.