Review
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Jun 9, 2024; 13(2): 92751
Published online Jun 9, 2024. doi: 10.5492/wjccm.v13.i2.92751
Major liver resections, perioperative issues and posthepatectomy liver failure: A comprehensive update for the anesthesiologist
Andrea De Gasperi, Laura Petrò, Ombretta Amici, Ilenia Scaffidi, Pietro Molinari, Caterina Barbaglio, Eva Cibelli, Beatrice Penzo, Elena Roselli, Andrea Brunetti, Maxim Neganov, Alessandro Giacomoni, Paolo Aseni, Elena Guffanti
Andrea De Gasperi, Former Head, Anesthesia and Critical Care Service 2, Grande Ospedale Metropolitano Niguarda ASST GOM Niguarda, Milan 20163, Italy
Laura Petrò, AR1, Ospedale Papa Giovanni 23, Bergamo 24100, Italy
Ombretta Amici, Ilenia Scaffidi, Pietro Molinari, Caterina Barbaglio, Eva Cibelli, Beatrice Penzo, Elena Roselli, Andrea Brunetti, Elena Guffanti, Anesthesia and Critical Care Service 2, Grande Ospedale Metropolitano Niguarda AR2, ASST GOM Niguarda, Milan 20163, Italy
Maxim Neganov, Anestesia e Terapia Intensiva Generale, Istituto Clinico Humanitas, Rozzano 20089, Italy
Alessandro Giacomoni, Chirurgia Oncologica Miniinvasiva, Grande Ospedale Metropolitano Niguarda ASST GOM Niguarda, Milan 20163, Italy
Paolo Aseni, Dipartimento di Medicina d’Urgenza ed Emergenza, Grande Ospedale Metropolitano Niguarda ASST GOM Niguarda, Milano 20163, MI, Italy
Co-first authors: Laura Petrò and Ombretta Amici.
Author contributions: De Gasperi A, Petrò L Amici O designed the review plan; De Gasperi A wrote the manuscript; Scaffidi I, Molinari P, Cibelli E, Barbaglio C equally contributed to bibliographic research, Penzo B, Neganov M, Roselli E, Brunetti A Guffanti E equally contributed in analyzing the various aspects of perioperative anesthesia management; Aseni P and Giacomoni A (surgeons) developed and wrote the anatomical and surgical issues; All the Authors have read and approved the manuscript.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Andrea De Gasperi, MD, Anesthesia and Critical Care Service 2, Grande Ospedale Metropolitano Niguarda ASST GOM Niguarda, Piazza Ospedale Maggiore 2, Milan 20163, Italy. dottdega@gmail.com
Received: February 12, 2024
Revised: March 15, 2024
Accepted: May 7, 2024
Published online: June 9, 2024
Processing time: 112 Days and 3 Hours
Core Tip

Core Tip: Aim of our review is, highlighting surgical anatomy of the liver, types of liver resection, and systemic consequences of surgical maneuvers, to provide the anesthesiologists involved in liver surgery with the expertise for a proactive management of the perioperative period. We will address cardiovascular consequences of vascular clamping and declamping, intraoperative hemodynamic monitoring, postoperative treatment of posthepatectomy liver failure, the use, if and when appropriate, of artificial support(s) and, in very selected cases, the rescue indication to liver transplant.