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World J Crit Care Med. Nov 9, 2021; 10(6): 323-333
Published online Nov 9, 2021. doi: 10.5492/wjccm.v10.i6.323
Extracorporeal membrane oxygenation and inhaled sedation in coronavirus disease 2019-related acute respiratory distress syndrome
Martin Bellgardt, Dennis Özcelik, Andreas Friedrich Christoph Breuer-Kaiser, Claudia Steinfort, Thomas Georg Karl Breuer, Thomas Peter Weber, Jennifer Herzog-Niescery
Martin Bellgardt, Andreas Friedrich Christoph Breuer-Kaiser, Thomas Peter Weber, Jennifer Herzog-Niescery, Anesthesia and Intensive Care Medicine, St. Josef-Hospital, University Hospital of Ruhr-University of Bochum, Bochum 44791, Germany
Dennis Özcelik, Chemistry | Biology | Pharmacy Information Center, ETH Zürich, Zürich 8093, Switzerland
Claudia Steinfort, General and Visceral Surgery, St. Josef-Hospital, University Hospital of Ruhr-University of Bochum, Bochum 44791, Germany
Thomas Georg Karl Breuer, Internal Medicine/Intensive Care, St. Josef-Hospital, University Hospital of Ruhr-University of Bochum, Bochum 44791, Germany
Author contributions: Bellgardt M designed and conceptualized this work; Bellgardt M, Özcelik D, and Herzog-Niescery J conducted the literature review and information retrieval and contributed to critical revision for important intellectual content; All authors wrote, read, and approved the final manuscript.
Conflict-of-interest statement: There is no conflict of interest associated with any of the authors of this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Martin Bellgardt, MD, Academic Research, Senior Scientist, Staff Physician, Anesthesia and Intensive Care Medicine, St. Josef-Hospital, University Hospital of Ruhr-University of Bochum, Gudrunstr. 56, Bochum 44791, Germany. martin.bellgardt@rub.de
Received: March 8, 2021
Peer-review started: March 8, 2021
First decision: May 13, 2021
Revised: May 24, 2021
Accepted: August 23, 2021
Article in press: August 23, 2021
Published online: November 9, 2021
Processing time: 241 Days and 12.9 Hours
Core Tip

Core Tip: This article summarizes the use of inhaled sedation for extracorporeal membrane oxygenation in patients suffering from coronavirus disease 2019 (COVID-19) related acute respiratory distress syndrome, including a description of respiratory management, the technical aspects, and requirements for delivery of volatile anesthetics. The article closes with important future considerations for inhaled sedation in critically ill COVID-19 patients undergoing extracorporeal membrane oxygenation therapy.