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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Surg Proced. Mar 28, 2015; 5(1): 155-166
Published online Mar 28, 2015. doi: 10.5412/wjsp.v5.i1.155
Published online Mar 28, 2015. doi: 10.5412/wjsp.v5.i1.155
Operative management of acute diverticulitis in immunosuppressed compared to immunocompetent patients: A systematic review
Ahmed Al-Khamis, Jad Abou Khalil, Marie Demian, Philip H Gordon, Marylise Boutros, Division of Colorectal Surgery, Jewish General Hospital, McGill University, Montreal, Quebec H3T 1E2, Canada
Nazi Torabi, Schulich Library of Science and Engineering, McGill University, Montreal, Quebec H3A 0C1, Canada
Abbas Kezouh, Department of Statistics and Epidemiology, Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada
Author contributions: Al-Khamis A and Khalil JA made the substantial contributions to conception and design of the study, acquisition of data, and analysis and interpretation of data; drafting the article; Torabi N contributed to conception and design of the study, acquisition of data; making critical revisions related to important intellectual content of the manuscript; Demian M contributed to acquisition of data, drafting the article; Kezouh A contributed to review of the statistical methods; Gordon PH and Boutros M contributed to conception and design of the study, acquisition of data, and analysis and interpretation of data; making critical revisions related to important intellectual content of the manuscript.
Conflict-of-interest: We have no relevant disclosures.
Data sharing: Review protocol and dataset available from the corresponding author at mboutros@jgh.mcgill.ca. Consent was not required nor obtained but the presented data are anonymized and risk of identification is low.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Marylise Boutros, MD, FRCS(C), Division of Colorectal Surgery, Jewish General Hospital, McGill University, 3755 Cote Ste Catherine G-314, Montreal, Quebec H3T 1E2, Canada. mboutros@jgh.mcgill.ca
Telephone: +1-514-3408222 Fax: +1-514-3407560
Received: October 9, 2014
Peer-review started: October 9, 2014
First decision: November 14, 2014
Revised: December 4, 2014
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: March 28, 2015
Processing time: 175 Days and 13.6 Hours
Peer-review started: October 9, 2014
First decision: November 14, 2014
Revised: December 4, 2014
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: March 28, 2015
Processing time: 175 Days and 13.6 Hours
Core Tip
Core tip: Immunosuppressed (IMS) patients present with more severe episodes of diverticulitis compared to immunocompetent patients and are at increased risk of an emergency operation. However, IMS patients have a vague disease presentation with insidious onset. The postoperative morbidity and mortality following emergency operations for diverticulitis is worse in the IMS patient population, whereas, in the elective setting, the morbidity and mortality is comparable to the general population.