Exploring the relationship between gut microbial ecology and inflammatory disease: An insight into health and immune function

doi:10.5411/wji.v14.i1.96209

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World Journal of Immunology

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World J Immunol. Jul 25, 2024; 14(1): 96209
Published online Jul 25, 2024. doi: 10.5411/wji.v14.i1.96209

Exploring the relationship between gut microbial ecology and inflammatory disease: An insight into health and immune function

Akashlina Marik, Saheli Biswas, Ena Ray Banerjee

Akashlina Marik, Saheli Biswas, Ena Ray Banerjee, Department of Zoology, University of Calcutta, Kolkata 700019, West Bengal, India

Co-first authors: Akashlina Marik and Saheli Biswas.

Author contributions: Ray Banerjee E conceptualized and wrote the manuscript; Marik A and Biswas S did the literature survey, designed and wrote the manuscript.

Supported by Council of Scientific and Industrial Research (CSIR), New Delhi; Department of Zoology, University of Calcutta for Infrastructural Support.

Conflict-of-interest statement: All the authors declare that they have no conflict of interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Ena Ray Banerjee, DSc, Professor, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, West Bengal, India. enarb1@gmail.com

Received: April 29, 2024
Revised: May 29, 2024
Accepted: June 27, 2024
Published online: July 25, 2024
Processing time: 86 Days and 13.5 Hours

Core Tip

Core Tip: The gut microbiome is a complex assemblage of microorganisms consisting of bacteria, archaea, fungi which inhabits the gut and are responsible for carrying out various functions like digestion of complex food components, synthesis of vitamins, stimulation of immune response and strengthening of gut barrier and protection from pathogens. Metabolites secreted by these bacteria play an important role in homeostasis and in maintaining a healthy state in the host. Dysbiosis of the intricately woven ecological networks in the gut microbiome plays a critical role in various health-related disorders like diabetes, obesity, and inflammatory bowel disease.