Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Pediatr. Sep 9, 2026; 15(3): 119162
Published online Sep 9, 2026. doi: 10.5409/wjcp.119162
Published online Sep 9, 2026. doi: 10.5409/wjcp.119162
Severe malaria-bacterial sepsis co-infection among critically ill children admitted to pediatric emergency departments in Kinshasa
Mamy-Gloire Monkoti Manzi, Celestin Nsibu, Joseph Bodi, Department of Pediatric, University Clinics of Kinshasa, Kinshasa 123, Congo
Mamy-Gloire Monkoti Manzi, Celestin Nsibu, Joseph Bodi, Department of Pediatric, University of Kinshasa, Kinshasa 123, Congo
Philippe Jouvet, Department of Pediatric, Sainte-Justine University Hospital, Montreal Montreal H3T 1C5, Quebec, Canada
Author contributions: Monkoti Manzi MG and Nsibu C designed the study; Monkoti Manzi MG, Nsibu C, and Bodi J collected the data; Monkoti Manzi MG and Jouvet P analyzed the data; Monkoti Manzi MG drafted the manuscript; Nsibu C, Bodi J, and Jouvet P critically revised the manuscript; and all authors read and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of School of Public Health, University of Kinshasa, Democratic Republic of Congo, approval No. ESP/CE/047/14.
Informed consent statement: Parents or legal guardians were informed of the use of anonymized clinical data for research purposes, in accordance with local ethical standards.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets generated and/or analyzed during the current study are available from the corresponding author upon reasonable request. The data are not publicly available due to ethical and confidentiality considerations.
Corresponding author: Mamy-Gloire Monkoti Manzi, MD, Lecturer, Department of Pediatric, University Clinics of Kinshasa, University Avenue, Lemba, Kinshasa 123, Congo.
Received: January 20, 2026
Revised: February 10, 2026
Accepted: April 14, 2026
Published online: September 9, 2026
Processing time: 192 Days and 11.6 Hours
Revised: February 10, 2026
Accepted: April 14, 2026
Published online: September 9, 2026
Processing time: 192 Days and 11.6 Hours
Core Tip
Core Tip: Among children admitted with severe malaria, concomitant bacterial sepsis is not uncommon and may be missed at presentation, contributing to early mortality. In pediatric emergency departments in Kinshasa, simple clinical signs-particularly respiratory distress-may help identify children at higher risk of co-infection, supporting early sepsis assessment and prompt integrated management in resource-limited settings.