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World J Clin Pediatr. Mar 9, 2026; 15(1): 116331
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.116331
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.116331
Effects of omega-3 fatty acid supplementation on heart rate variability
Hoda Atef Abdelsattar Ibrahim, Division of Pediatric Clinical Nutrition, Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo 12613, Egypt
Kamal Gouda Kamal, Mohamed Khaled Ali Mohamed Ali Zid, Albraa Ashraf Hamad, Ayesha Kuraishi, Undergraduate students, Dr. Hoda Atef Abdelsattar Ibrahim’s Research Group, Faculty of Medicine, Cairo University, Cairo 12613, Egypt
Marwa Taha, Department of Pediatrics, Mataria Teaching Hospital, General Organization for Teaching Hospitals and Institutes, Cairo 11756, Egypt
Author contributions: Atef Abdelsattar Ibrahim H contributed to the visualization, conceptualization, the database search, data formal statistical analysis, data interpretation, and manuscript drafting, writing, reviewing, and editing; Kamal KG and Zid MKAMA contributed to the database search; Hamad AA contributed to reviewing and editing; Kuraishi A contributed to manuscript drafting, writing, reviewing, and editing; Taha M contributed to the database search, manuscript drafting, writing, critical reviewing, and editing; All authors have read and approved the final manuscript.
Conflict-of-interest statement: There are no conflicts of interest to declare.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Hoda Atef Abdelsattar Ibrahim, Affiliate Associate Professor, Division of Pediatric Clinical Nutrition, Department of Pediatrics, Faculty of Medicine, Cairo University, No. 1 Gamaa Street, Giza, Cairo 12613, Egypt. hodaibrahim424@gmail.com
Received: November 10, 2025
Revised: November 25, 2025
Accepted: January 5, 2026
Published online: March 9, 2026
Processing time: 118 Days and 8.3 Hours
Revised: November 25, 2025
Accepted: January 5, 2026
Published online: March 9, 2026
Processing time: 118 Days and 8.3 Hours
Core Tip
Core Tip: Overweight and obesity have become serious global health concerns that frighteningly impact both adults and children. Obesity is intimately linked to decreased heart rate variability (HRV), which is considered a non-invasive indicator of cardiovascular risk. Omega-3 fatty acids supplementation acts as a promising adjuvant cardio-protective therapy that may improve time-domain HRV in the overweight and obese individuals.