Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.113152
Revised: September 11, 2025
Accepted: December 24, 2025
Published online: March 9, 2026
Processing time: 202 Days and 12.8 Hours
Core Tip: Juvenile idiopathic arthritis (JIA) can lead to irreversible structural and functional damage. The juvenile arthritis damage index (JADI) emerges as a valuable tool for assessing long-term joint involvement and guiding therapeutic strategies. In addition to predicting pharmacological response, JADI offers specific advantages over disease activity scores-such as juvenile arthritis disease activity score-because it reflects irreversible damage rather than active inflammation, making it particularly relevant for long-term rehabilitation planning. Beyond predicting pharmacological response, JADI enables the identification of patients with established lesions who require tailored rehabilitation. Early integration of individualized physical exercise and physiotherapy with medical treatment may restore function, prevent further deterioration, and enhance adherence. Incorporating JADI into clinical practice optimizes exercise prescription, mobility, and quality of life in patients with JIA.
