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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Dec 9, 2025; 14(4): 107290
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.107290
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.107290
Features of patients with uveitis associated with juvenile idiopathic arthritis required eye surgery
Alexandr Alexandrovich Yakovlev, Ekaterina Vladimirovna Gaidar, Lyubov Sergeevna Sorokina, Irina Alexandrovna Chikova, Olga Valerievna Kalashnikova, Mikhail Mikhailovich Kostik, Hospital Pediatry, Saint-Petersburg State Pediatric Medical University, Saint Petersburg 194100, Russia
Tatiana Nikolaevna Nikitina, Department of Ophthalmology, Saint-Petersburg State Pediatric Medical University, Saint Petersburg 194100, Russia
Author contributions: Yakovlev AA and Kostik MM contributed to conceptualization, writing, reviewing, and editing; Yakovlev AA contributed to formal analysis; Gaidar EV and Kostik MM contributed to methodology; Gaidar EV, Sorokina LS, Nikitina TN, and Chikova IA contributed to investigation and visualization; Nikitina TN contributed to validation; Kalashnikova OV contributed to software, resources, and data curation; Kostik MM contributed to supervision and project administration; All authors read and agreed to the published version of the manuscript.
Institutional review board statement: The protocol of the study was approved by the Ethical Committee of Saint-Petersburg State Pediatric Medical University, No. 3114.
Informed consent statement: Informed consent was obtained from all subjects involved in the study.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mikhail Mikhailovich Kostik, MD, PhD, Professor, Hospital Pediatry, Saint-Petersburg State Pediatric Medical University, Lytovskaya 2, Saint Petersburg 194100, Russia. kost-mikhail@yandex.ru
Received: March 25, 2025
Revised: April 27, 2025
Accepted: July 7, 2025
Published online: December 9, 2025
Processing time: 221 Days and 4.4 Hours
Revised: April 27, 2025
Accepted: July 7, 2025
Published online: December 9, 2025
Processing time: 221 Days and 4.4 Hours
Core Tip
Core Tip: Uveitis, a vision-threatening condition associated with juvenile idiopathic arthritis, requires rapid control of intraocular inflammation. There is limited information in the literature regarding patients with juvenile idiopathic arthritis-associated uveitis who have undergone surgical treatment, making our study a unique contribution. According to the obtained data, patients who have undergone surgical treatment for uveitis or its complications require more aggressive therapy, including the use of biological disease-modifying antirheumatic drugs. Additionally, it is important to consider that early methotrexate administration in this patient group may be associated with a decreased probability of surgical inter