©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Mar 9, 2025; 14(1): 102254
Published online Mar 9, 2025. doi: 10.5409/wjcp.v14.i1.102254
Published online Mar 9, 2025. doi: 10.5409/wjcp.v14.i1.102254
Systematic comparison of Kawasaki disease Z-score formulas: Enhancing diagnostic accuracy and clinical applicability across populations
Yan Pan, Department of Pediatrics, The First Affiliated Hospital of Yangtze University, Jingzhou 434000, Hubei Province, China
Fu-Yong Jiao, Shaanxi Kawasaki Disease Diagnosis and Treatment Center, Children's Hospital, Shaanxi Provincial People's Hospital of Xi'an, Jiaotong Univeristy, Xi'an 710000, Shaanxi Province, China
Author contributions: Jiao FY designed the research study; Pan Y designed the research study, performed the research, contributed new reagents and analytic tools, analyzed the data, wrote the manuscript, read and approve the final manuscript.
Conflict-of-interest statement: The authors declare no conflict of interest.
Corresponding author: Fu-Yong Jiao, PhD, Shaanxi Kawasaki Disease Diagnosis and Treatment Center, Children's Hospital, Shaanxi Provincial People's Hospital of Xi'an, Jiaotong Univeristy, No. 256 Youyi West Road, Beilin District, Xi'an 710000, Shaanxi Province, China. 3105089948@qq.com
Received: October 12, 2024
Revised: November 2, 2024
Accepted: November 19, 2024
Published online: March 9, 2025
Processing time: 68 Days and 8.6 Hours
Revised: November 2, 2024
Accepted: November 19, 2024
Published online: March 9, 2025
Processing time: 68 Days and 8.6 Hours
Core Tip
Core Tip: Kawasaki disease (KD) is a critical pediatric vasculitis, with coronary artery lesions (CALs) as its most severe complication. The coronary artery Z-score is a valuable metric for assessing coronary dilation in KD patients. This paper reviews six Z-score calculation formulas, with a focus on their clinical applicability in different populations. A retrospective study from Suzhou, China, shows that the Kobayashi and Dallaire formulas offer the best sensitivity and accuracy for Chinese children, leading to better diagnostic outcomes and improved management of CALs.