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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Nov 9, 2022; 11(6): 437-454
Published online Nov 9, 2022. doi: 10.5409/wjcp.v11.i6.437
Published online Nov 9, 2022. doi: 10.5409/wjcp.v11.i6.437
Cow’s milk-induced gastrointestinal disorders: From infancy to adulthood
Mohammed Al-Beltagi, Department of Pediatrics, Faculty of Medicine, Tanta University, Tanta 31511, Algharbia, Egypt
Mohammed Al-Beltagi, Department of Pediatrics, University Medical Center, Arabian Gulf University, Manama 26671, Bahrain
Nermin Kamal Saeed, Department of Pathology, Microbiology Section, Salmaniya Medical Complex, Manama 26671, Bahrain
Nermin Kamal Saeed, Department of Pathology, Microbiology Section, Royal College of Surgeons in Ireland - Bahrain, Busaiteen 15503, Muharraq, Bahrain
Adel Salah Bediwy, Department of Chest Diseases, Faculty of Medicine, Tanta University, Tanta 31527, Algharbia, Egypt
Adel Salah Bediwy, Department of Chest Diseases, University Medical Center, Arabian Gulf University, Manama 26671, Bahrain
Reem Elbeltagi, Department of Medicine, The Royal College of Surgeons in Ireland - Bahrain, Busiateen 15503, Muharraq, Bahrain
Author contributions: Al-Beltagi M, Saeed NK, Bediwy AS, and Elbeltagi R collected the data and wrote and revised the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mohammed Al-Beltagi, MBChB, MD, MSc, PhD, Academic Editor, Chairman, Consultant Physician-Scientist, Professor, Researcher, Department of Pediatrics, Faculty of Medicine, Tanta University, Al Bahr Street, Tanta 31511, Algharbia, Egypt. mbelrem@hotmail.com
Received: August 14, 2022
Peer-review started: August 14, 2022
First decision: August 29, 2022
Revised: September 1, 2022
Accepted: October 14, 2022
Article in press: October 14, 2022
Published online: November 9, 2022
Processing time: 84 Days and 10.7 Hours
Peer-review started: August 14, 2022
First decision: August 29, 2022
Revised: September 1, 2022
Accepted: October 14, 2022
Article in press: October 14, 2022
Published online: November 9, 2022
Processing time: 84 Days and 10.7 Hours
Core Tip
Core Tip: Milk has been a basic human food for hundreds of centuries with a high nutritional value. However, milk can cause various gastrointestinal disorders from early childhood to late adulthood, as many milk ingredients, such as lactose and cow’s milk proteins, can trigger gastrointestinal discomfort and disorders. Cow’s milk protein allergy and lactose intolerance are the most common milk-related disorders. However, milk consumption is related to many functional gastrointestinal disorders, inflammatory bowel disease, milk-related cancer, and milk-born zoonotic infections. Awareness of these disorders is crucial for physicians and patients to avoid unnecessary nutritional mismanagement.