Current methods of staging and restaging of the mediastinal nodes in non-small-cell lung cancer

doi:10.5320/wjr.v5.i2.166

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World Journal of Respirology

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2218-6255

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Respirol. Jul 28, 2015; 5(2): 166-175
Published online Jul 28, 2015. doi: 10.5320/wjr.v5.i2.166

Table 1 Diagnostic yield of staging procedures in non-small-cell lung cancer (%)

Diagnostic technique	SensitivityMean (range)	SpecificityMean (range)	Negative predictive value Mean (range)
Chest CT	55 (20-91)	81 (50-97)	83 (54-97)
PET/CT	77 (33-100)	86 (43-100)	91 (79-100)
EBUS/TBNA	89 (46-97)	100 (96-100)	91 (60-99)
EUS/FNA	89 (45-100)	100 (90-100)	86 (68-100)
Mediastinoscopy	78 (32-92)	100	91 (80-97)
Video-mediastinoscopy	89 (78-97)	100	92 (83-96)
VATS	99 (58-100)	100	96 (88-100)
VAMLA	93.8	100	96
TEMLA	96.2	100	98.9

CT: Computer tomography; PET: Positron emission tomography; EBUS/TBNA: Endobronchial ultrasound/transbronchial needle aspiration; EUS/FNA: Endoscopic ultrasound/fine needle aspiration; VAMLA: Video-assisted mediastinoscopic lymphadenectomy; TEMLA: Transcervical extended mediastinal lymphadenectomy; VATS: Video-assisted thoracic surgery.

Table 2 Diagnostic yield of restaging procedures in non-small-cell lung cancer after neoadjuvant therapy (%)

Diagnostic technique	SensitivityMean (range)	SpecificityMean (range)	Negative predictive valueMean (range)
Chest CT	55 (20-91)	81 (50-97)	83 (54-97)
PET/CT	77 (33-100)	86 (43-100)	91 (79-100)
EBUS/TBNA	89 (46-97)	100 (96-100)	91 (60-99)
EUS/FNA	89 (45-100)	100 (90-100)	86 (68-100)
Mediastinoscopy	78 (32-92)	100	91 (80-97)
Video-mediastinoscopy	89 (78-97)	100	92 (83-96)
VATS	99 (58-100)	100	96 (88-100)
VAMLA	93.8	100	96
TEMLA	96.2	100	98.9

Citation: Zielinski M. Current methods of staging and restaging of the mediastinal nodes in non-small-cell lung cancer. World J Respirol 2015; 5(2): 166-175
URL: https://www.wjgnet.com/2218-6255/full/v5/i2/166.htm
DOI: https://dx.doi.org/10.5320/wjr.v5.i2.166