Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hematol. Sep 19, 2024; 11(3): 98807
Published online Sep 19, 2024. doi: 10.5315/wjh.v11.i3.98807
Multifaceted role of haptoglobin: Implications for disease development
Chun-Han Cheng, Wen-Rui Hao, Tzu-Hurng Cheng
Chun-Han Cheng, Department of Medical Education, Linkou Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan
Wen-Rui Hao, Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, New Taipei 23561, Taiwan
Wen-Rui Hao, Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11002, Taiwan
Tzu-Hurng Cheng, Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, Taichung 404328, Taiwan
Co-corresponding authors: Wen-Rui Hao and Tzu-Hurng Cheng.
Author contributions: Cheng CH wrote the editorial, including synthesizing recent research findings and developing the manuscript’s key themes; Hao WR and Cheng TH provided critical revisions and guidance throughout the drafting process; all authors have read and approved the final version.
Conflict-of-interest statement: The authors declare that they having have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tzu-Hurng Cheng, PhD, Professor, Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, No. 91 Xueshi Road, North District, Taichung 404328, Taiwan. thcheng@mail.cmu.edu.tw
Received: July 6, 2024
Revised: August 29, 2024
Accepted: September 6, 2024
Published online: September 19, 2024
Processing time: 74 Days and 21.3 Hours
Core Tip

Core Tip: This editorial elucidates the under-recognized functions of haptoglobin beyond its established role in hemoglobin sequestration. By highlighting its contributions to inflammatory processes, immune regulation, and the pathogenesis of chronic diseases, this editorial indicates the importance of further research to fully elucidate its therapeutic potential. A comprehensive understanding of haptoglobin’s multifaceted nature may facilitate the development of innovative diagnostic and therapeutic interventions to enhance patient outcomes in various diseases.