Treatment options for patients with advanced osteoarthritis who decline knee surgery

doi:10.5312/wjo.v17.i4.114991

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Apr 18, 2026 (publication date) through Apr 16, 2026

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. Apr 18, 2026; 17(4): 114991
Published online Apr 18, 2026. doi: 10.5312/wjo.v17.i4.114991

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Figure 1 An overview of non-surgical treatment strategies for knee osteoarthritis in patients unwilling or unable to undergo surgery, highlighting the link between including guideline-recommended treatments, and emerging interventions available to clinicians. OA: Osteoarthritis; NSAIDs: Nonsteroidal anti-inflammatory drugs; RFA: Radiofrequency ablation; GAE: Genicular artery embolization; GLP-1RA: Glucagon-like peptide-1 receptor agonist; K-L: Kellgren-Lawrence.

Citation: Kacprzak J, Kołaczyński R, Surma A, Sokalski D, Adamus JP, Pulik Ł, Łęgosz P. Treatment options for patients with advanced osteoarthritis who decline knee surgery. World J Orthop 2026; 17(4): 114991
URL: https://www.wjgnet.com/2218-5836/full/v17/i4/114991.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i4.114991