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World J Orthop. Oct 18, 2025; 16(10): 110562
Published online Oct 18, 2025. doi: 10.5312/wjo.v16.i10.110562
Figure 1
Figure 1 Number of publications in the PubMed database from 2000 to 2024. A: Studies on bone repair using alginate as the main biomaterial; B: Studies on cartilage restoration (joints) using alginate as the main biomaterial.
Figure 2
Figure 2  The current application of alginate in various fields.
Figure 3
Figure 3  The metabolic pathway of alginate biosynthesis.
Figure 4
Figure 4 Alginate-RGD hydrogels. A: Alginate-RGD hydrogel substrate for studying the adhesion of mesenchymal stem cells (MSCs) in 2D; B: Encapsulated MSCs in an alginate-RGD hydrogel for studying their differentiation in 3D.
Figure 5
Figure 5  This is a summary of the development and application of alginate-based biomaterials as injectable hydrogels for cartilage regeneration.