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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2025; 16(10): 110562
Published online Oct 18, 2025. doi: 10.5312/wjo.v16.i10.110562
Published online Oct 18, 2025. doi: 10.5312/wjo.v16.i10.110562
Alginate-based biomaterials in orthopedics: What are the prospects for bacterial alginate?
Andrei A Dudun, Garina A Bonartseva, A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russia
Andrei A Dudun, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow 123098, Russia
Anton P Bonartsev, Faculty of Biology, M.V. Lomonosov Moscow State University, Moscow 119234, Russia
Author contributions: Dudun AA wrote the manuscript; Bonartsev AP reviewed and edited the manuscript; and Bonartseva GA designed the research study and approved the final manuscript. All authors have read and approved the final manuscript.
Supported by Russian Science Foundation, No. 23-74-10027.
Conflict-of-interest statement: Bonartsev AP reports grants from Russian Science Foundation, during the conduct of the study; grants from NF Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, outside the submitted work.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Anton P Bonartsev, PhD, Associate Professor, Faculty of Biology, M.V. Lomonosov Moscow State University, Leninskie Gory 1, Bld 12, Moscow 119234, Russia.
Received: June 11, 2025
Revised: July 1, 2025
Accepted: September 9, 2025
Published online: October 18, 2025
Processing time: 128 Days and 16.3 Hours
Revised: July 1, 2025
Accepted: September 9, 2025
Published online: October 18, 2025
Processing time: 128 Days and 16.3 Hours
Core Tip
Core Tip: The mini-review explores the potential use of alginates produced biotechnologically by bacteria of genus Azotobacter and Pseudomonas for the development of various implantable hydrogel biomaterials intended for bone and cartilage tissue rege