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World J Orthop. Mar 18, 2025; 16(3): 102930
Published online Mar 18, 2025. doi: 10.5312/wjo.v16.i3.102930
Osteosarcopenia and geriatric hip fractures: Current concepts
Theodoros Tosounidis, Lefteris Manouras, Byron Chalidis
Theodoros Tosounidis, Academic Department of Orthopaedic Surgery, Heraklion University Hospital, University of Crete, Heraklion 71500, Greece
Lefteris Manouras, Department of Orthopaedic Surgery, University Hospital Heraklion, Heraklion 71500, Greece
Byron Chalidis, First Academic Orthopaedic Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 57010, Greece
Author contributions: Tosounidis T and Chalidis B designed the research; Manouras L and Tosounidis T analyzed the data and wrote the paper; Tosounidis T and Chalidis B critically revised the manuscript.; all authors read and approved the final manuscript.
Conflict-of-interest statement: All authors have nothing to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Byron Chalidis, MD, PhD, Assistant Professor, First Academic Orthopaedic Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Exohi, Thessaloniki 57010, Greece. byronchalidis@gmail.com
Received: November 4, 2024
Revised: February 9, 2025
Accepted: February 19, 2025
Published online: March 18, 2025
Processing time: 130 Days and 10.6 Hours
Core Tip

Core Tip: Osteosarcopenia is a major geriatric issue affecting hip fracture patients. Its true prevalence is unknown whilst it is associated with increased mortality. Future research should focus on the exploration of the molecular pathways involved in the pathogenesis of osteosarcopenia and the development of recommendations regarding the prevention, pharmacological treatment and optimal management of the syndrome.