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Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2024; 15(10): 918-931
Published online Oct 18, 2024. doi: 10.5312/wjo.v15.i10.918
Application prospects of urine-derived stem cells in neurological and musculoskeletal diseases
Hui-Si Yang, Yue-Xiang Zheng, Xue Bai, Xiu-Ying He, Ting-Hua Wang
Hui-Si Yang, Yue-Xiang Zheng, Xue Bai, Ting-Hua Wang, Department of Neurology and National Traditional Chinese Medicine Clinical Research Base, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Xiu-Ying He, Department of Anesthesiology, Institute of Neurological Disease, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Ting-Hua Wang, Department of Anesthesiology, Institute of Neurological Disease, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Co-first authors: Hui-Si Yang and Yue-Xiang Zheng.
Co-corresponding authors: Xiu-Ying He and Ting-Hua Wang.
Author contributions: Yang HS, Zheng YX, Bai X, He XY and Wang TH contributed to conceptualization, outline creation, literature review, writing-original draft preparation, and writing-reviewing and editing.
Supported by the Key Research and Development Program of Sichuan Science and Technology Agency, No. 2020YFS0043; Natural Science Foundation of Sichuan Province of China, No. 2023NSFSC1567; Sichuan University Innovation Research Project, No. 2023SCUH0033; and Innovation Team at the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, No. 2022-CXTD-05.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ting-Hua Wang, PhD, Professor, Department of Neurology and National Traditional Chinese Medicine Clinical Research Base, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China. wangth_email@163.com
Received: April 24, 2024
Revised: August 25, 2024
Accepted: September 9, 2024
Published online: October 18, 2024
Processing time: 169 Days and 18.3 Hours
Core Tip

Core Tip: Urine-derived stem cells and urine-derived induced pluripotent stem cells possess high potential of neurogenic, myogenic, and osteogenic differentiation, which are able to be used for the treatment of neurological and musculoskeletal disorders.