Published online Feb 18, 2026. doi: 10.5312/wjo.v17.i2.113696
Revised: October 2, 2025
Accepted: December 10, 2025
Published online: February 18, 2026
Processing time: 156 Days and 13.5 Hours
Various factors affecting the outcomes after primary total knee arthroplasty (TKA) have been investigated in the literature; however, the effect of surgeon hande
To assess whether the radiological and functional outcomes differ between right and left primary TKA when operated by right-handed surgeons.
A retrospective evaluation of 370 TKAs performed by right-handed surgeons [47.8% right TKAs, dominant side (Group D), and 52.2% left TKAs, non-dominant side (Group N)]. The radiological outcomes were the overall alignment measured as the hip-knee-ankle (HKA) angle, and the tibial and femoral component ali
There were no difference in patients' basic characteristics or in postoperative radiological or functional outcomes between Group D and Group N as follows: HKA, 177.96° ± 3.13° vs 178.55° ± 3.38° (P = 0.082), MPTA, 88.90° ± 2.61° vs 89.43° ± 2.71° (P = 0.056), mLDFA, 90.16° ± 2.54° vs 89.76° ± 2.53° (P = 0.140), and KSS, 80.59 ± 14.73 vs 79.56 ± 15.64 (P = 0.628). There was no significant difference in the percentage of outliers in the HKA and mLDFA between groups. For the MPTA, Group D had significantly more implants within the safe zone than Group N, 53.7% vs 41.4% (P = 0.022). There was no difference regarding using intramedullary (IM) vs extramedullary (EM) alignment for the tibial cut between both groups (P = 0.687). In Group D, there was no significant difference in mean MPTA between IM (88.86° ± 3.26°) and EM (88.93° ± 1.76°) methods (P = 0.862); however, EM resulted in significantly fewer outliers compared to IM (29.2% vs 63.6% respectively; P < 0.001). In Group N, the EM method produced a significantly more valgus alignment than IM (90.38° ± 1.99° vs 88.56° ± 3.00°, P < 0.001), but this did not translate into a significant reduction in outliers (P = 0.650).
The overall radiological and functional outcomes after primary TKA were unaffected by the surgeon's handedness; however, the placement of the tibial component was significantly more precise on the dominant side with fewer outliers.
Core Tip: Factors affecting primary total knee arthroplasty (TKA) outcomes could be related to the patient, surgical technique, and the surgeon. One rarely investigated surgeon-related factor is surgeon handedness. We evaluated 370 knees operated by right-handed surgeons, where 177 TKAs were right (dominant side) and 193 were left (non-dominant side). We found no difference between sides regarding the overall limb and individual component coronal plane alignment; furthermore, there was no difference in the functional outcomes between sides, but there were fewer tibial component outliers in the dominant side. Surgeons operating on the non-dominant side should pay attention during the tibial cut and implant insertion.
