Published online Sep 18, 2025. doi: 10.5312/wjo.v16.i9.111218
Revised: July 10, 2025
Accepted: August 1, 2025
Published online: September 18, 2025
Processing time: 77 Days and 2.7 Hours
Crush syndrome demands an integrated multidisciplinary approach that spans acute surgical decisions and long-term functional recovery. In response to Khan et al’s recent systematic review, we propose complementary perspectives that address two underrepresented dimensions: Vascular surgical decision-making and psychiatric rehabilitation. We emphasize the use of intraoperative technologies such as indocyanine green fluorescence angiography and compartment pressure monitoring to guide limb salvage strategies and reperfusion manage
Core Tip: This letter expands on Khan et al’s review by emphasizing two often overlooked aspects of crush syndrome: Intraoperative vascular decision-making and psychiatric rehabilitation. We highlight the use of perfusion assessment tools and tailored anticoagulation strategies to improve limb salvage. Additionally, we advocate for early screening of post-traumatic stress disorder (PTSD), depression, and anxiety using validated tools like PTSD Checklist for DSM 5 and Patient Health Questionnaire 9. These additions aim to integrate surgical precision with trauma-informed mental health care, supporting a more holistic and outcome-focused approach to managing crush injuries, especially in disaster and high-impact trauma settings.
