Bioactive substances with anti-neoplastic efficacy from marine invertebrates: Porifera and Coelenterata

Table 1 The most important bioactive substances with anti-neoplastic effects isolated from Porifera

Component	Species	Ref.
Durissimols	Strongylophora durissima	[32]
Plakorsin B	Plakortis simplex	[32]
Chondrillin	Xestospongia sp.	[32]
Neopeltolide	Neopeltidae	[33]
Jaspolide		[37,38]
Dolastatin		[37,38]
Halichondrin		[37,38]
Spongistatin		[37,38]
Hemiasterlin		[37,38]
Dictyostatin		[37,38]
Discodermolide		[37,38]
Laulimalide		[37,38]
Peloruside A		[37,38]
Zampanolide		[37,38]
Lamellarins		[39]
Sodwanone	Axinella sp.,	[10]
Triterpenoids	Axinella sp.,	[10]
Furanolipid	Axinella sp.,	[10]
Homoscalarane sesterterpenes	Axinella sp.,	[10]
Norsesterterpenes	Axinella sp.,	[10]
Diacarnoxides	Axinella sp.,	[10]
Strongylophorines	Petrosia strongylata	[10]
Stelletin A	Jaspis stellifera	[44]
Agelasines	Agela sp.	[46]
Asmarines	Agela sp.	[46]
Dragmacidin	Dragmacidin sp.,	[48]
Nortopsentins	Spongosorites ruetzleri	[48]
Topsentins	Topsentia genitrix	[49]
Hyrtinadine	Hyrtios sp.	[50]
Hyrtosins	Hyrtios sp.	[50]
Hyrtioerectines	Hyrtios reticulates	[50]
Hytriocarboline	Hyrtios reticulates	[50]
Cylindradines	Axinella cylindratus	[52]
Agelastatins	Agelas dendromorpha	[53]
Dibromophakellstatin	Phakellia mauritiana	[54]

Table 2 The most important bioactive substances with anti-neoplastic effects isolated from coelenterata

Component	Species	Ref.
Cervicosides	Sinularia cervicornis	[31]
Claviridenones	Clavularia viridis	[31]
Dollabelane	Nepheta sp.	[57]
Xenicane	Nepheta sp.	[57]
Phenylgermacrane	Nepheta sp.	[57]
Clavulactones	Clavularia sp.	[57]
Clavirolides	Clavularia sp.	[57]
Clavudiols	Clavularia sp.	[57]
Cembrane	Sinularia sp.	[59]
Eleutherobin	Eleutherobia sp.	[60]
Sarcodictyin	Sarcodictyon roseum	[62]
Menverins	Menella verrucosa	[65]