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Case Control Study
©The Author(s) 2026.
World J Clin Oncol. Feb 24, 2026; 17(2): 114431
Published online Feb 24, 2026. doi: 10.5306/wjco.v17.i2.114431
Table 1 Patients demographic characteristics in two groups, median (interquartile range)/n (%)
Demographic characteristics
Control group (n = 65)
EA group (n = 65)
Year52 (43.5-61)52 (43.5-61.5)
Height (cm)156 (151.5-160)155 (152-159)
Weight (kg)55 (50-60.25)57 (51.25-67.75)
Combined disease29 (44.60)36 (55.40)
Breast cancer location
Right29 (44.60)33 (50.80)
Left36 (55.40)32 (49.20)
Basic information of operation
Incoming (mL)1000 (1000-1000)1000 (1000-1000)
Output (mL)120 (30-230)110 (20-250)
Anesthesia time (minutes)240 (190-285)240 (189.5-277.5)
Operation procedure
Partial resection + sentinel lymph node biopsy7 (5.38)8 (6.16)
Partial resection + axillary dissection9 (6.92)8 (6.16)
Total mastectomy + sentinel lymph node biopsy36 (27.69)30 (23.08)
Total mastectomy + axillary dissection18 (13.85)14 (10.76)
Table 2 Occurrence of postoperative pain in two groups
Time after surgeryn (moderate/severe pain) (%)
VAS score (mean ± SD)
Control group
EA group
Control group
EA group
24 hours after surgery
Pain during exercise41/1 (64.6)30/2 (49.2)a3.954 ± 0.2332.862 ± 0.233b
Pain at rest11/1 (18.5)7/1 (12.3)2.692 ± 0.1741.789 ± 0.174b
48 hours after surgery
Pain during exercise29/0 (44.6)24/1 (38.5)2.108 ± 0.181.785 ± 0.18
Pain at rest6/0 (9.2)5/0 (7.7)1.169 ± 0.1190.631 ± 0.119
72 hours after surgery
Pain during exercise19/0 (29.2)16/0 (24.6)1.215 ± 0.121.115 ± 0.12
Pain at rest2/0 (3.1)3/0 (4.6)0.631 ± 0.080.415 ± 0.086
Table 3 Basic living ability scores 24 hours post-surgery in two groups, median (interquartile range)
BADL item
Control group (n = 65)
EA group (n = 65)
Eating10 (10-10)10 (10-10)
Bathing0 (0-2.5)0 (0-5)
Grooming0 (0-5)5 (5-5)b
Dressing5 (5-10)10 (5-10)b
Controlling defecation10 (5-10)10 (10-10)
Controlling urination10 (5-10)10 (10-10)
Toileting10 (5-10)10 (10-10)a
Transferring15 (10-15)15 (10-15)a
Walking15 (15-15)15 (15-15)
Climbing up and down the stairs5 (0-5)5 (0-10)
Total score80 (65-87.5)85 (75-90)b
Table 4 Postoperative complications in two groups, n (%)
Complication
Control group
EA group
Dizziness5 (7.8)4 (6.2)
Appetite loss36 (55.4)27 (41.5)a
Postoperative nausea and vomiting22 (33.8)13 (20.0)a
Diarrhoea4 (6.2) 4 (6.2)
Constipation4 (6.2)4 (6.2)