Histologic subtypes of non-muscle invasive bladder cancer

Table 1 Classification of tumors of the urinary tract

Category	Features
Urothelial tumors	Invasive urothelial neoplasms: (1) Conventional urothelial carcinoma; (2) Urothelial carcinoma with squamous differentiation; (3) Urothelial carcinoma with glandular differentiation; (4) Urothelial carcinoma with trophoblastic differentiation; (5) Nested urothelial carcinoma; (6) Large nested urothelial carcinoma; (7) Tubular and microcystic urothelial carcinomas; (8) Micropapillary urothelial carcinoma; (9) Lymphoepithelioma-like urothelial carcinoma; (10) Plasmacytoid urothelial carcinoma; (11) Giant cell urothelial carcinoma; (12) Lipid-rich urothelial carcinoma; (13) Clear cell (glycogen-rich) urothelial carcinoma; (14) Sarcomatoid urothelial carcinoma; and (15) Poorly differentiated urothelial carcinoma
	Noninvasive urothelial neoplasms: (1) Urothelial papilloma; (2) Urothelial papilloma, inverted; (3) Papillary urothelial neoplasm of low malignant potential; (4) Inverted papillary urothelial neoplasm of low malignant potential; (5) Noninvasive papillary urothelial carcinoma, low grade; (6) Low-grade papillary urothelial carcinoma with an inverted growth pattern; (7) Noninvasive papillary urothelial carcinoma, high grade; (8) Noninvasive high-grade papillary urothelial carcinoma with an inverted growth pattern; and (9) Urothelial carcinoma in situ
Nonurothelial tumors	(1) Squamous cell neoplasms of the urinary tract; (2) Glandular neoplasms; (3) Adenocarcinomas; (4) Urachal and diverticular neoplasms; (5) Urethral neoplasms; and (6) Tumors of Mullerian type