Predicting colorectal cancer prognosis based on long noncoding RNAs of disulfidptosis genes

doi:10.5306/wjco.v15.i1.89

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Jan 24, 2024 (publication date) through Nov 8, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Clin Oncol. Jan 24, 2024; 15(1): 89-114
Published online Jan 24, 2024. doi: 10.5306/wjco.v15.i1.89

Table 1 Primers for disulfidptosis-related lncRNAs/Genes

LncRNA/Gene	Forward primer	Reverse primer
AC005034.5	TGCAAGGTGTCATCTGTAAGG	TGACAGTTCCAACAGGGCTA
AC011815.1	GGCCAGCGACAGATCCTTT	TGGCCCACTGTTGCCATCAA
AC013652.1	AGGGCATCAGACTGCATTTCA	GACAAGCAGAAAATGGGGCA
AC093157.1	GAGATGGGCAAGCCTACACC	TGGGTCCAGAAAGAAGTTGC
AL354993.2	TGCATTCCAGAGGGAGGAGA	CCACTCCTTGGAAGCTGTCT
AL683813.1	GCGGCTGAGTTTCTGACTCT	GTTTGGGATACAGGAGGCCG
TNFRSF10A-AS1	TCAGTGATAGCAACAGAAAACAG	ACTGCACCTAGCCAAGATGTC
TCAP	GAGTTCCCAAAGGGAGGGTG	TTTTCCTGGATCAGGGCCAC
NNAT	AATCAAAACACCGCACCAGC	ACCACCCTCCTTCCTCAACT
CHGB	GGTCCTCTCAAGGAGGGAGT	AGTGGGTTGAATGGTGGTCC
COL2A1	GCTCCCAGAACATCACCTACC	CGATAACAGTCTTGCCCCAC
β-actin	CGCGAGAAGATGCCCAGATC	TCACCGGAGTCCATCACGA

Table 2 Clinical characteristics of colorectal cancer patients in the training and testing groups, n (%)

Covariates	Type	Total	Test	Train	P value
Age	≤ 70	312 (57.56)	160 (59.04)	152 (56.09)	0.543
Age	> 70	230 (42.44)	111 (40.96)	119 (43.91)	-
Gender	FEMALE	255 (47.05)	137 (50.55)	118 (43.54)	0.1214
Gender	MALE	287 (52.95)	134 (49.45)	153 (56.46)	-
Stage	StageI	93 (17.16)	43 (15.87)	50 (18.45)	0.3949
Stage	StageII	208 (38.38)	100 (36.9)	108 (39.85)	-
Stage	StageIII	148 (27.31)	82 (30.26)	66 (24.35)	-
Stage	StageIV	78 (14.39)	36 (13.28)	42 (15.5)	-
Stage	Unknow	15 (2.77)	10 (3.69)	5 (1.85)	-
T	T1	15 (2.77)	6 (2.21)	9 (3.32)	0.8475
T	T2	93 (17.16)	45 (16.61)	48 (17.71)	-
T	T3	370 (68.27)	188 (69.37)	182 (67.16)	-
T	T4	63 (11.62)	32 (11.81)	31 (11.44)	-
T	Unknow	1 (0.18)	0 (0)	1 (0.37)	-
M	M0	402 (74.17)	205 (75.65)	197 (72.69)	0.4435
M	M1	77 (14.21)	35 (12.92)	42 (15.5)	-
M	Unknow	63 (11.62)	31 (11.44)	32 (11.81)	-
N	N0	318(58.67)	154 (56.83)	164 (60.52)	0.5238
N	N1	129 (23.8)	70 (25.83)	59 (21.77)	-
N	N2	94 (17.34)	46 (16.97)	48 (17.71)	-
N	Unknow	1 (0.18)	1 (0.37)	0 (0)	-

Citation: Wang KL, Chen KD, Tang WW, Chen ZP, Wang YJ, Shi GP, Chen YG. Predicting colorectal cancer prognosis based on long noncoding RNAs of disulfidptosis genes. World J Clin Oncol 2024; 15(1): 89-114
URL: https://www.wjgnet.com/2218-4333/full/v15/i1/89.htm
DOI: https://dx.doi.org/10.5306/wjco.v15.i1.89