Role of liver transplantation in the management of colorectal liver metastases: Challenges and opportunities

Table 1 Study characteristics and findings

A. Early experience
Author, Yr	Study period	Number of patients	Clinical outcomes
Mühlbacher et al[24], 1991	1982-1994	25	1-yr OS: 76%, 3-yr OS: 32%, 5-yr OS: 12%
Penn et al[27], 1991	N/A	10	70% recurrence rate
Pichlmayr et al[28], 1997	1972-1995	4	2 post-operative mortalities, 2 late mortalities due to recurrence
B. Recent era
Author, Yr	Study period	Number of patients	Follow-up	1-yr OS, %	3-yr OS, %	5-yr OS, %	DFS
Hagness et al[30], 2013	2006-2011	21	27 mo	95	68	60	35% at 1st year
Dueland et al[41], 2020	2012-2016	15	36 mo	100	83	83	13.7 mo
Smedman et al[21], 2020	2014-2018	10	23 mo	N/A	N/A	N/A	4 mo
Toso et al[31], 2017	1995-2015	12	26 mo	83	62	50	56% at 1st year

All values reported for continuous variables are expressed in median. OS: Overall survival; DFS: Disease free survival, N/A: Not available.