©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Oct 10, 2017; 8(5): 420-424
Published online Oct 10, 2017. doi: 10.5306/wjco.v8.i5.420
Published online Oct 10, 2017. doi: 10.5306/wjco.v8.i5.420
First report of small cell lung cancer with PTHrP-induced hypercalcemic pancreatitis causing disconnected duct syndrome
Eric M Montminy, Jordan J Karlitz, Division of Gastroenterology, Tulane University Medical Center, New Orleans, LA 70112, United States
Stephen W Landreneau, Division of Gastroenterology, LSU Health Sciences Center, New Orleans, LA 70112, United States
Author contributions: Montminy EM and Landreneau SW wrote manuscript and directly cared for the patient while hospitalized; Karlitz JJ was overseeing author and provided edits to manuscript.
Informed consent statement: The patient discussed in this case report gave written consent to share imaging and discuss his medical information. This consent was witnessed.
Conflict-of-interest statement: All authors had no conflicts of interests.
Correspondence to: Eric M Montminy, MD, Internal Medicine Resident, Tulane University Medical Center, 1430 Tulane Avenue, SL-50, New Orleans, LA 70112, United States. emontmin@tulane.edu
Telephone: +1-630-3060555 Fax: +1-504-9883971
Received: June 2, 2017
Peer-review started: June 6, 2017
First decision: June 27, 2017
Revised: July 5, 2017
Accepted: August 16, 2017
Article in press: August 17, 2017
Published online: October 10, 2017
Processing time: 114 Days and 4.4 Hours
Peer-review started: June 6, 2017
First decision: June 27, 2017
Revised: July 5, 2017
Accepted: August 16, 2017
Article in press: August 17, 2017
Published online: October 10, 2017
Processing time: 114 Days and 4.4 Hours
Core Tip
Core tip: Acute recurrent pancreatitis flares should raise concern for disconnected duct syndrome (DDS). This case is the first reported case of DDS caused by paraneoplastic hypercalcemia. Paraneoplastic syndromes may predispose patients to prolonged hypercalcemic pancreatitis and in turn, may predispose patients to DDS. Furthermore, this case report reviews the current approach and treatment difficulties of DDS as well as pancreatic walled-off necrosis.