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World J Clin Oncol. Oct 10, 2014; 5(4): 595-603
Published online Oct 10, 2014. doi: 10.5306/wjco.v5.i4.595
Published online Oct 10, 2014. doi: 10.5306/wjco.v5.i4.595
Surgical strategies in the therapy of non-small cell lung cancer
Feras Al-Shahrabani, Daniel Vallböhmer, Sebastian Angenendt, Wolfram T Knoefel, Department of Surgery A, Section of Thoracic Surgery, Heinrich Heine University and University Hospital, 40225 Düsseldorf, NRW, Germany
Author contributions: Al-Shahrabani F, Vallböhmer D, Angenendt S and Knoefel WT substantial contributed to conception and design, acquisition of data, or analysis and interpretation of data; drafting the article or revising it critically for important intellectual content; and final approval of the version to be published.
Correspondence to: Dr. Wolfram T Knoefel, Professor, Department of Surgery A, Section of Thoracic Surgery, Heinrich Heine University and University Hospital, Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, NRW, Germany. knoefel@uni-duesseldorf.de
Telephone: +49-21-18117351 Fax: +49-21-18117359
Received: April 15, 2014
Revised: June 6, 2014
Accepted: June 27, 2014
Published online: October 10, 2014
Processing time: 108 Days and 7.4 Hours
Revised: June 6, 2014
Accepted: June 27, 2014
Published online: October 10, 2014
Processing time: 108 Days and 7.4 Hours
Core Tip
Core tip: Lung cancer represents the leading cause of cancer mortality worldwide. To date, surgical resection is the primary mode of treatment for stage I and II non-small cell lung cancer (NSCLC) and has become an important component of the multimodality therapy of even more advanced disease with a curative intention. In fact, individualized treatment options, based on clinical tumor stages, in NSCLC patients have been established in the last years that are displayed in this review.