Evolving patterns of gastrointestinal stromal tumor presentation, management, and outcome over three decades: A Middle Eastern retrospective study
Moamena Ahmed El-Matbouly, Hassan Al-Thani, Ayman El-Menyar, Maryam Al-Sulaiti, Mohammad Asim, Mohammad Al Yaseen, Ahmed Suliman, Ahmed Albahrani, Issam Al-Bozom, Abdelhakem Tabeb
Moamena Ahmed El-Matbouly, Hassan Al-Thani, Ayman El-Menyar, Maryam Al-Sulaiti, Mohammad Al Yaseen, Ahmed Suliman, Ahmed Albahrani, Abdelhakem Tabeb, Department of Surgery, Hamad Medical Corporation, Doha 3050, Qatar
Ayman El-Menyar, Clinical Medicine, Weill Cornell Medicine, Doha 24144, Qatar
Ayman El-Menyar, Mohammad Asim, Department of Surgery, Trauma Surgery, Clinical Research, Hamad Medical Corporation, Doha 3050, Qatar
Issam Al-Bozom, Department of Clinical Pathology and Laboratory Medicine, Hamad Medical Corporation, Doha 3050, Qatar
Co-first authors: Moamena Ahmed El-Matbouly and Hassan Al-Thani.
Author contributions: El-Matbouly MA, Al-Thani H, and El-Menyar A contributed to conceptualization; El-Matbouly MA, Al-Thani H, Al-Sulaiti M, Asim M, Al Yaseen M, Suliman A, Albahrani A, Al-Bozom I, and Tabeb A contributed to methodology; El-Matbouly MA, Al-Thani H, Al Yaseen M, Suliman A, Albahrani A, Al-Bozom I, and Tabeb A contributed to data curation; Asim M, and El-Menyar A contributed to formal analysis; El-Matbouly MA, Al-and Thani H contributed to writing-original draft preparation; El-Matbouly MA, Al-Thani H, Al Yaseen M, Suliman A, Albahrani A, Al-Bozom I, Tabeb A, El-Menyar A, and Asim M contributed to writing review and editing. All authors have read and agreed to the published version of the manuscript. El-Matbouly MA and Al-Thani H contributed equally to this work as co-first authors.
AI contribution statement: Grammarly was used only for language polishing.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Hamad Medical Corporation, Doha, Qatar, No. 13269/13, No. MRC-01-20-958 and No. MRC-01-25-1067.
Informed consent statement: This study was approved with a waiver of informed consent from the medical research center at Hamad Medical Corporation, Doha, Qatar IRB 13269/13; MRC-01-20-958 and MRC-01-25-1067), as data were collected anonymously, retrospectively, and without direct contact with patients.
Conflict-of-interest statement: The authors declare no conflict of interest.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: All data are presented in the manuscript, figures, and tables. It will be available upon reasonable request and upon approval by the medical research center of Hamad Medical Corporation, upon signing a data-sharing agreement form.
Corresponding author: Ayman El-Menyar, MD, Department of Surgery, Hamad Medical Corporation, Al-Rayyan Street, Doha 3050, Qatar.
aymanco65@yahoo.com
Received: February 25, 2026
Revised: March 11, 2026
Accepted: May 22, 2026
Published online: June 24, 2026
Processing time: 117 Days and 12.1 Hours
