Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. May 24, 2025; 16(5): 104762
Published online May 24, 2025. doi: 10.5306/wjco.v16.i5.104762
Yttrium-90 radioembolization for advanced hepatocellular carcinoma with Budd-Chiari syndrome: A case report
Ming-Hua Shao, Bin-Bin Tan, Hai-Lei Chen, Hui Zhang
Ming-Hua Shao, Bin-Bin Tan, Hai-Lei Chen, Hui Zhang, Department of Hepatobiliary Surgery, First Affiliated Hospital of Third Military Medical University (Army Medical University), Chongqing 400038, China
Author contributions: Zhang H, Shao MH, and Tan BB conceptualized the paper, wrote the abstract, introduction, and case presentation sections of the paper, and created the literature review table; Zhang H, Shao MH, and Chen HL contributed to the case discussion; Zhang H provided essential input in reviewing the manuscript for important intellectual content, and supervised and assisted with the final editing; and all authors thoroughly reviewed and endorsed the final manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui Zhang, Chief Physician, Department of Hepatobiliary Surgery, First Affiliated Hospital of Third Military Medical University (Army Medical University), No. 30 Gaotanyan Main Street, Shapingba Distirct, Chongqing 400038, China. 13637912611@163.com
Received: January 8, 2025
Revised: March 4, 2025
Accepted: April 22, 2025
Published online: May 24, 2025
Processing time: 131 Days and 23.6 Hours
Core Tip

Core Tip: This case report highlights the successful combination of yttrium-90 radioembolization therapy and lenvatinib in treating a patient with advanced hepatocellular carcinoma characterized by large tumors, multiple intrahepatic metastases, and Budd-Chiari syndrome complicated by chronic hepatic failure. Despite the complexity of the case, this treatment approach effectively reduced tumor burden, improved liver function, and significantly prolonged the patient’s survival, offering a promising therapeutic option for similar challenging scenarios.