©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Apr 24, 2025; 16(4): 103343
Published online Apr 24, 2025. doi: 10.5306/wjco.v16.i4.103343
Published online Apr 24, 2025. doi: 10.5306/wjco.v16.i4.103343
Overview of serrated polyposis syndrome from pathophysiology, diagnosis, and management
Zong-Yang Li, Tong Li, Hong-Qiao Cai, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Cai HQ designed the overall concept and outline of the manuscript; Li ZY contributed to the discussion and design of the manuscript; Li T and Cai HQ contributed to the writing, and editing the manuscript, illustrations, and review of literature.
Conflict-of-interest statement: The authors have claimed no conflicts.
Corresponding author: Hong-Qiao Cai, MD, PhD, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. hongqiaocai@jlu.edu.cn
Received: November 18, 2024
Revised: January 24, 2025
Accepted: February 14, 2025
Published online: April 24, 2025
Processing time: 129 Days and 10.3 Hours
Revised: January 24, 2025
Accepted: February 14, 2025
Published online: April 24, 2025
Processing time: 129 Days and 10.3 Hours
Core Tip
Core Tip: Serrated polyposis syndrome (SPS) is a rare and clinically significant condition, marked by the presence of multiple serrated colorectal polyps, significantly increasing the risk of colorectal cancer (CRC). By a comprehensive overview of its pathophysiology, clinical manifestations, diagnostic criteria, management strategies, and the psychosocial impact on patients, a more individualized surveillance approach to minimize the risk of CRC associated with SPS should be developed.