Systemic oncological therapy in breast cancer patients on dialysis

doi:10.5306/wjco.v15.i6.730

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Jun 24, 2024 (publication date) through Feb 13, 2026

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World Journal of Clinical Oncology

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World J Clin Oncol. Jun 24, 2024; 15(6): 730-744
Published online Jun 24, 2024. doi: 10.5306/wjco.v15.i6.730

Systemic oncological therapy in breast cancer patients on dialysis

Salman Khan, Ghada Araji, Ekrem Yetiskul, Praneeth Reddy Keesari, Fadi Haddadin, Zaid Khamis, Varun Chowdhry, Muhammad Niazi, Sarah Afif, Meekoo Dhar, Suzanne El-Sayegh

Salman Khan, Ghada Araji, Ekrem Yetiskul, Praneeth Reddy Keesari, Fadi Haddadin, Zaid Khamis, Varun Chowdhry, Suzanne El-Sayegh, Department of Internal Medicine, Northwell Health - Staten Island University Hospital, Staten Island, NY 10305, United States

Muhammad Niazi, Meekoo Dhar, Department of Hematology and Oncology, Northwell Health - Staten Island University Hospital, Staten Island, NY 10305, United States

Sarah Afif, Department of Internal Medicine, CUNY School of Medicine, New York, NY 10031, United States

Author contributions: Khan S, Araji G, Yetiskul E, Keesari PR, Haddadin F, Khamis Z, Chowdhry V, Afif S, Dhar M, and El-Sayegh S designed the research study and performed the research, and contributed new reagents and analytic tools; Khan S, Araji G, Yetiskul E, Keesari PR, Haddadin F, Khamis Z, Chowdhry V, Niazi M, Afif S, Dhar M, and El-Sayegh S analyzed the data and wrote the manuscript; and all authors have read and approved the final manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Salman Khan, MD, Academic Fellow, Academic Research, Department of Internal Medicine, Northwell Health - Staten Island University Hospital, 475 Seaview Ave, Staten Island, NY 10305, United States. skhan114@northwell.edu

Received: March 24, 2024
Revised: May 12, 2024
Accepted: May 29, 2024
Published online: June 24, 2024
Processing time: 91 Days and 10.1 Hours

Core Tip

Core Tip: Optimizing systemic breast cancer therapy in dialysis patients requires tailored approaches due to altered drug clearance and dialysis sessions’ necessity. This review emphasizes the significance of optimizing dosing and administration strategies, ensuring both efficacy and safety. Challenges in breast cancer screening, including soft-tissue calcifications, are highlighted, underlining the necessity for precise diagnostic strategies in this population. Furthermore, nuanced understanding and guidelines are imperative to navigate the complexity of oncological treatment in dialysis patients, ultimately enhancing patient outcomes.