Narayan S, Talwar V, Goel V, Chaudhary K, Sharma A, Redhu P, Soni S, Jain A. Co-relation of SARS-CoV-2 related 30-d mortality with HRCT score and RT-PCR Ct value-based viral load in patients with solid malignancy. World J Clin Oncol 2022; 13(5): 339-351 [PMID: 35662981 DOI: 10.5306/wjco.v13.i5.339]
Corresponding Author of This Article
Varun Goel, DNB, Doctor, Consultant Physician-Scientist, Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5 Rohini, Sir Chhotu Ram Marg, New Delhi 110085, India. drvarungoyaloncologist@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Satya Narayan, Vineet Talwar, Varun Goel, Krushna Chaudhary, Pallavi Redhu, Satyajeet Soni, Arpit Jain, Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi 110085, India
Anurag Sharma, Department of Research, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi 110085, India
Author contributions: Narayan S and Talwar V were involved in design of study and the acquisition of data; Goel V, Chaudhary K, Redhu P, Soni S, Jain A were involved in the drafting and revision of the manuscript; Narayan S and Sharma A were involved in the statistical calculation; All authors discussed and contributed to the final manuscript.
Institutional review board statement: The study has been approved by our Institutional Review Board (RGCIRC/Res/SCM/46 2021/95) and was conducted according to the Declaration of Helsinki.
Conflict-of-interest statement: Authors have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Varun Goel, DNB, Doctor, Consultant Physician-Scientist, Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5 Rohini, Sir Chhotu Ram Marg, New Delhi 110085, India. drvarungoyaloncologist@gmail.com
Received: October 3, 2021 Peer-review started: October 3, 2021 First decision: November 19, 2021 Revised: November 30, 2021 Accepted: April 25, 2022 Article in press: April 25, 2022 Published online: May 24, 2022 Processing time: 233 Days and 2 Hours
Core Tip
Core Tip: There is a higher fatality rate in cancer patients as compared to non-cancer patients. Also, a higher incidence of serious clinical events and intensive care unit (ICU) admissions in cancer patients. Analysis suggests patients have increased morbidity and mortality from recent cytotoxic chemotherapy. Patients with active untreated cancer, metastatic disease, progressive disease with multiple co-morbidity as well as getting palliative treatment are at a higher risk of mortality. Mortality rates are higher in patients with high baseline HRCT values at presentation and need longer ICU stays. Mortality rates are not a statistically significant co-relation with higher baseline RT-PCR based viral load values at presentation. Mortality rates are not higher in older cancer patients as compared to younger counterparts with cancer.
