Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Nov 24, 2021; 12(11): 1072-1082
Published online Nov 24, 2021. doi: 10.5306/wjco.v12.i11.1072
Anaplastic myxopapillary ependymoma: A case report and review of literature
Hiroshi Kanno, Yukiko Kanetsuna, Masamichi Shinonaga
Hiroshi Kanno, Masamichi Shinonaga, Department of Neurosurgery, International University of Health and Welfare Atami Hospital, Atami 413-0012, Shizuoka, Japan
Yukiko Kanetsuna, Department of Pathology, International University of Health and Welfare Atami Hospital, Atami 413-0012, Shizuoka, Japan
Author contributions: Kanetsuna Y performed the histological evaluation; Kanno H drafted the manuscript, the table and figures; Shinonaga M evaluated the clinical data and reviewed the manuscript.
Informed consent statement: Written informed consent was obtained from the patient before surgical treatment. In addition, all procedures performed in this study were in accordance with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Conflict-of-interest statement: The authors declare no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hiroshi Kanno, MD, PhD, Professor, Surgical Oncologist, Department of Neurosurgery, International University of Health and Welfare Atami Hospital, 13-1 East Coast, Atami 413-0012, Shizuoka, Japan. hiroshikannomd@nifty.com
Received: February 23, 2021
Peer-review started: February 23, 2021
First decision: May 4, 2021
Revised: May 5, 2021
Accepted: October 11, 2021
Article in press: October 11, 2021
Published online: November 24, 2021
Processing time: 269 Days and 0.6 Hours
Core Tip

Core Tip: Myxopapillary ependymoma (MPE) is a pathological grade I tumor that develops in the filum terminale. MPEs with anaplastic features are extremely rare; only 5 cases have shown malignancy when they relapsed. Here we report a case of MPE with anaplastic features in local late recurrence in a 46-year-old woman and review anaplastic MPE in the published literature. MPEs have the potential for malignant transformation after a long period of time despite being a pathological grade I tumor. Therefore, the possibility of malignant transformation of the MPE should be considered, and patients with MPE should be treated carefully and monitored over a long period of time.