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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Dec 24, 2020; 11(12): 983-989
Published online Dec 24, 2020. doi: 10.5306/wjco.v11.i12.983
Published online Dec 24, 2020. doi: 10.5306/wjco.v11.i12.983
Stereotactic body radiation therapy: A good dance partner of oligometastatic non-small cell lung cancer to the sound of SINDAS study
Xabier Mielgo-Rubio, Department of Medical Oncology, Hospital Universitario Fundación Alcorcón, Madrid 28922, Spain
Javier Garde-Noguera, Department of Medical Oncology, Hospital Arnau de Vilanova, C/Sant Climent, Valencia 46015, Spain
Oscar Juan, Department of Medical Oncology, La Fe University Hospital, Valencia 46026, Comunitat Valenciana, Spain
Oscar Juan, School of Medicine, Catholic University San Vicente Martir, Valencia 46001, Comunitat Valenciana, Spain
Felipe Couñago, Department of Radiation Oncology, Hospital Universitario Quirónsalud Madrid, Hospital La Luz, Universidad Europea de Madrid, Madrid 28028, Spain
Author contributions: All authors contributed equally to the manuscript.
Conflict-of-interest statement: Mielgo-Rubio X has received fees for serving as a speaker, a consultant and/or an advisory board member for BMS, Roche, MSD, Kiowa Kirin, Astra Zeneca, Boehringer Ingelheim, Abbott. Mielgo-Rubio X hast received research funding from BMS for a ISR.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Oscar Juan, MD, PhD, Attending Doctor, Senior Researcher, Department of Medical Oncology, La Fe University Hospital, Valencia 46026, Comunitat Valenciana, Spain. ojjuanv@seom.org
Received: July 25, 2020
Peer-review started: July 25, 2020
First decision: October 6, 2020
Revised: October 21, 2020
Accepted: October 27, 2020
Article in press: October 27, 2020
Published online: December 24, 2020
Processing time: 146 Days and 0.1 Hours
Peer-review started: July 25, 2020
First decision: October 6, 2020
Revised: October 21, 2020
Accepted: October 27, 2020
Article in press: October 27, 2020
Published online: December 24, 2020
Processing time: 146 Days and 0.1 Hours
Core Tip
Core Tip: In this editorial, we review the definitions and historical context of advanced non-small cell lung cancer with oligometastatic disease. We also review the scientific evidence for local ablative therapy and stereotactic body radiation therapy as well as the results of recently-published prospective studies. Finally, we provide an in-depth analysis of the interim results of the SINDAS trial, particularly its strengths and weaknesses, and the barriers to extrapolating these findings to real-life clinical practice.