©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Nov 24, 2019; 10(11): 375-381
Published online Nov 24, 2019. doi: 10.5306/wjco.v10.i11.375
Published online Nov 24, 2019. doi: 10.5306/wjco.v10.i11.375
Radiation-induced malignant rhabdoid tumour of the hypothalamus in an adult: A case report
Pei-Meng Ng, Peh-Hueh Low, Donald Ngian-San Liew, Albert Sii-Hieng Wong, Department of Neurosurgery, Sarawak General Hospital, Kuching 93586, Sarawak, Malaysia
Author contributions: Ng PM and Low PH reviewed the literature and contributed to manuscript drafting; Wong ASH and Liew DNS were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient’s parent for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Peh-Hueh Low, MBBS, Neurosurgeon, Department of Neurosurgery, Sarawak General Hospital, Kuching 93586, Sarawak, Malaysia. peh.hueh@gmail.com
Telephone: +60-19-2188599
Received: May 23, 2019
Peer-review started: May 23, 2019
First decision: August 2, 2019
Revised: October 10, 2019
Accepted: October 15, 2019
Article in press: October 15, 2019
Published online: November 24, 2019
Processing time: 187 Days and 11.8 Hours
Peer-review started: May 23, 2019
First decision: August 2, 2019
Revised: October 10, 2019
Accepted: October 15, 2019
Article in press: October 15, 2019
Published online: November 24, 2019
Processing time: 187 Days and 11.8 Hours
Core Tip
Core tip: Malignant rhabdoid tumours of the central nervous system are highly malignant, with a grave prognosis. Occurrence in adults is extremely rare. Due to the paucity of available data, treatment recommendations for adults are derived mainly from paediatric data. Despite being a dismal disease, prognosis in children has been more encouraging recently due to the continuous refinement of treatment strategies. We report a case of malignant rhabdoid tumour in an adult with presumed radiation-induced aetiology, with the hope to enrich the armamentarium of this disease entity and provide some implications for early diagnosis and treatment of this disease in the future.