Alfayez M. Primary small cell oesophageal carcinoma: A retrospective study of different treatment modalities. World J Clin Oncol 2020; 11(10): 836-843 [PMID: 33200076 DOI: 10.5306/wjco.v11.i10.836]
Corresponding Author of This Article
Mohammad Alfayez, MD, PhD, Assistant Professor, Faculty of Medicine, Umm Al-Qura University, Alabdeh campus, Makkah-Taif Road, Makkah 21514, Saudi Arabia. malfayez@nhs.net
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Cohort Study
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Alfayez M. Primary small cell oesophageal carcinoma: A retrospective study of different treatment modalities. World J Clin Oncol 2020; 11(10): 836-843 [PMID: 33200076 DOI: 10.5306/wjco.v11.i10.836]
World J Clin Oncol. Oct 24, 2020; 11(10): 836-843 Published online Oct 24, 2020. doi: 10.5306/wjco.v11.i10.836
Primary small cell oesophageal carcinoma: A retrospective study of different treatment modalities
Mohammad Alfayez
Mohammad Alfayez, Faculty of Medicine, Umm Al-Qura University, Makkah 21514, Saudi Arabia
Mohammad Alfayez, King Abdullah Medical City, Makkah 21514, Saudi Arabia
Mohammad Alfayez, Beatson West of Scotland Cancer Centre, Glasgow G12 0YN, United Kingdom
Author contributions: Alfayez M collected and analyzed the data, wrote the manuscript, read and approve the final manuscript.
Institutional review board statement: NHS Greater Glasgow and Clyde Ethics Committee has reviewed the research proposal for the study title primary small oesophageal cancer: A retrospective study of different modalities of treatment. The study is a historical cohort which was looking at the outcomes of patients with small cell of oesophagus who were treated at the Beatson West of Scotland Cancer Centre. There was no requirement to obtain ethical approval for such historical study.
Informed consent statement: Consent was not obtained but the presented data are anonymized and risk of identification is low.
Conflict-of-interest statement: The author has no conflict of interest related to the manuscript.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at malfayez@nhs.net. No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Corresponding author: Mohammad Alfayez, MD, PhD, Assistant Professor, Faculty of Medicine, Umm Al-Qura University, Alabdeh campus, Makkah-Taif Road, Makkah 21514, Saudi Arabia. malfayez@nhs.net
Received: June 16, 2020 Peer-review started: June 16, 2020 First decision: July 25, 2020 Revised: July 29, 2020 Accepted: September 11, 2020 Article in press: September 11, 2020 Published online: October 24, 2020 Processing time: 126 Days and 23.2 Hours
ARTICLE HIGHLIGHTS
Research background
Small cell oesophageal cancer (SCOC) is rare. Until now, there was no general consensus of optimal treatment in this group of patients.
Research motivation
Future RCT involving this small group population is a priority to determine best modality of treatment.
Research objectives
The main objective was to determine the best modality of treatment for patients diagnosed with SCOC.
Research methods
This is a retrospective analysis of different treatment modalities on this highly poor prognosis as well as a rare group of esophageal carcinoma.
Research results
The finding of this study will add to growing body of literature on the benefit of CCRT in the treatment of limited stage (LS) small cell cancer of esophagus.
Research conclusions
Patient with LS of oesophageal cancer with good performance status should be treated with Concurrent chemoradiation.
Research perspectives
The future research will involve prospective studies.
