Cripe J, Eskander R, Tewari K. Sentinel lymph node mapping of a breast cancer of the vulva: Case report and literature review. World J Clin Oncol 2015; 6(2): 16-21 [PMID: 25866706 DOI: 10.5306/wjco.v6.i2.16]
Corresponding Author of This Article
James Cripe, MD, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, the University of California, Irvine Medical Center, 101 the City Drive, Orange, CA 92701, United States. jccripe@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Oncol. Apr 10, 2015; 6(2): 16-21 Published online Apr 10, 2015. doi: 10.5306/wjco.v6.i2.16
Sentinel lymph node mapping of a breast cancer of the vulva: Case report and literature review
James Cripe, Ramez Eskander, Krishnansu Tewari
James Cripe, Ramez Eskander, Krishnansu Tewari, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, the University of California, Irvine Medical Center, Orange, CA 92701, United States
Author contributions: Cripe J, Eskander R and Tewari K contributed equally to this work; Cripe J drafted the manuscript; Eskander R made significant edits of intellectual content; Tewari K approved the overall works.
Ethics approval: The case report was approved by the University of California - Irvine.
Informed consent: The patient provided informed written consent prior to case review.
Conflict-of-interest: The authors have no financial or non-financial disclosures to make.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: James Cripe, MD, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, the University of California, Irvine Medical Center, 101 the City Drive, Orange, CA 92701, United States. jccripe@gmail.com
Telephone: +1-714-4566707
Received: December 24, 2014 Peer-review started: December 26, 2014 First decision: January 8, 2015 Revised: January 29, 2015 Accepted: February 10, 2015 Article in press: February 12, 2015 Published online: April 10, 2015 Processing time: 105 Days and 1.2 Hours
Abstract
Ectopic breast tissue is rare and typically presents as an axillary mass. Previous reports have identified ectopic breast tissue in the vulva, but malignancy is exceedingly uncommon. We present a 62 years old with locally advanced breast carcinoma arising in the vulva demonstrates the utilization of sentinel lymph node mapping to identify metastatic lymph nodes previously unable to be identified via traditional surgical exploration. Our case supports the principles of adjuvant therapy for breast cancer to be applied to ectopic breast cancer arising in the vulva. A literature review highlights common key points in similar cases to guide management.
Core tip: Our findings describe the presentation of ectopic breast cancer in the vulva. We demonstrate use of sentinel lymph node technology with identification of the sentinel node, only possible after the use of this technology. We conclude with a review of the literature outlining treatment of this enigmatic disease.
