Yakar M. Letter to the Editor: Patient-reported outcomes of intensity-modulated radiotherapy vs three-dimensional conformal radiotherapy in prostate cancer. World J Clin Oncol 2026; 17(7): 120006 [DOI: 10.5306/wjco.120006]
Corresponding Author of This Article
Melek Yakar, Associate Professor, Department of Radiation Oncology, Eskisehir Osmangazi University Faculty of Medicine, Odunpazarı Eskisehir, Turkey, Eskisehir 26040, Türkiye. mcakcay@ogu.edu.tr
Research Domain of This Article
Oncology
Article-Type of This Article
letter
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Yakar M. Letter to the Editor: Patient-reported outcomes of intensity-modulated radiotherapy vs three-dimensional conformal radiotherapy in prostate cancer. World J Clin Oncol 2026; 17(7): 120006 [DOI: 10.5306/wjco.120006]
World J Clin Oncol. Jul 24, 2026; 17(7): 120006 Published online Jul 24, 2026. doi: 10.5306/wjco.120006
Letter to the Editor: Patient-reported outcomes of intensity-modulated radiotherapy vs three-dimensional conformal radiotherapy in prostate cancer
Melek Yakar
Melek Yakar, Department of Radiation Oncology, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir 26040, Türkiye
Author contributions: Yakar M reviewed the relevant literature, interpreted the findings of the discussed study, and drafted and approved the final manuscript.
Conflict-of-interest statement: The author declares no conflict of interest in publishing the manuscript.
Corresponding author: Melek Yakar, Associate Professor, Department of Radiation Oncology, Eskisehir Osmangazi University Faculty of Medicine, Odunpazarı Eskisehir, Turkey, Eskisehir 26040, Türkiye. mcakcay@ogu.edu.tr
Received: February 12, 2026 Revised: March 9, 2026 Accepted: April 22, 2026 Published online: July 24, 2026 Processing time: 162 Days and 9.6 Hours
Abstract
In this study, published in the World Journal of Clinical Oncology by Mera et al, three-dimensional conformal radiotherapy and intensity-modulated radiotherapy were assessed with respect to patient-reported outcome measures in patients with localized prostate cancer. Furthermore, they used a prospective observational design and analyzed urinary, gastrointestinal, sexual, and quality-of-life end points using real-world outcomes, as opposed to dose-volume histograms or clinician-based toxicity scales. They use the patient-reported outcome measures to show how patients perceive radiotherapy technique, fractionation, dose escalation, and technology.
Core Tip: The study by Mera et al demonstrates that patient-reported outcome measures provide crucial information regarding the impact of radiotherapy planning techniques on patients with localized prostate cancer. Comparing three-dimensional conformal radiotherapy and intensity-modulated radiotherapy, the study suggests an association between radiotherapy technique and patient-reported functional outcomes rather than a direct causal relationship. Therefore, patient-reported outcome measures are highly important tools for evaluating treatment and technological advancements from a patient-centered perspective.
