Factors influencing postoperative of hypertension remission in adrenal cavernous hemangioma: A multicenter retrospective cohort study
Zheng-Guo Du, Yu-Yun Wu, Tomrry Homyy, Wen-Qian Zhao, Tersus Minsler, Siemmenjro Tekosiv, Thensyi Zhang, Chiize Song, Ting-Liu Tui, Shen-Tang Shi, Hong-Jun Tan, Savidy Jan, Shi-Jing Deng, Li-Ming Qiu, Thong-Xiao Su, Sajieli Teisy, Zan-Xiu Zhuang, Xiao-Jing Xie, Tian-Xin Qiu, Zhao-De Xiong, Tao-Xiang Lang, Xiu-Lu Zhen, Jin-Xia Qin, Xiang-Bo Zheng, Xarlos Teriguezs, Toolin Fie, Giutels Hasly, Cheng-Kun Duan, Chao-Hua Deng
Zheng-Guo Du, Department of Cardiology, The Fourth Affiliated Hospital of Dali University, Chuxiong 675000, Yunnan Province, China
Yu-Yun Wu, Third Ward, Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650500, Yunnan Province, China
Tomrry Homyy, Department of Urology, Johns Hopkins Hospital, Baltimore, MD 21201-9997, United States
Wen-Qian Zhao, Precision Medicine Center, The Fourth Affiliated Hospital of Dali University, Chuxiong 675000, Yunnan Province, China
Tersus Minsler, Department of Endocrinology, Peking University First Hospital, Beijing 100000, China
Siemmenjro Tekosiv, Department of Urology, Tianjin Medical University General Hospital, Tianjin 300000, China
Thensyi Zhang, Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China
Chiize Song, Department of Urology, The First Affiliated Hospital of China Medical University, Shenyang 110000, Liaoning Province, China
Ting-Liu Tui, Department of Endocrinology, The First Bethune Hospital of Jilin University, Changchun 130000, Jilin Province, China
Shen-Tang Shi, Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin 150010, Heilongjiang Province, China
Hong-Jun Tan, Department of Urology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China
Savidy Jan, Department of General Surgery, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200001, China
Shi-Jing Deng, Department of Urology, The First Affiliated Hospital of Zhejiang University, Hangzhou 310002, Zhejiang Province, China
Li-Ming Qiu, Department of Urology, Jiangsu Provincial People’s Hospital, Nanjing 210000, Jiangsu Province, China
Thong-Xiao Su, Department of Urology, Qilu Hospital of Shandong University, Jinan 250000, Shandong Province, China
Sajieli Teisy, Department of Radiology, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China
Zan-Xiu Zhuang, Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510000, Guangdong Province, China
Xiao-Jing Xie, Department of Endocrinology, Nanfang Hospital of Southern Medical University, Guangzhou 510000, Guangdong Province, China
Tian-Xin Qiu, Department of Urology, Sun Yat-sen Memorial Hospital Sun Yat-sen University, Guangzhou 510000, Guangdong Province, China
Zhao-De Xiong, Department of Urology, Hainan Provincial People’s Hospital, Haikou 570100, Hainan Province, China
Tao-Xiang Lang, Department of Urology, Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Xiu-Lu Zhen, Department of Endocrinology, Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Jin-Xia Qin, Department of Urology, Xiangya Hospital of Central South University, Changsha 410000, Hunan Province, China
Xiang-Bo Zheng, Department of Urology, West China Hospital of Sichuan University, Chengdu 610000, Sichuan Province, China
Xarlos Teriguezs, Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400000, China
Toolin Fie, Department of Urology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710000, Shaanxi Province, China
Giutels Hasly, Department of Urology, Xijing Hospital of Air Force Medical University, Xi’an 710000, Shaanxi Province, China
Cheng-Kun Duan, Department of Urology, The 950th Hospital of the Chinese People’s Liberation Army, Urumqi 830000, Xinjiang Uygur Autonomous Region, China
Chao-Hua Deng, Department of Urology, The Fourth Affiliated Hospital of Dali University, Chuxiong 675000, Yunnan Province, China
Co-first authors: Zheng-Guo Du and Yu-Yun Wu.
Co-corresponding authors: Cheng-Kun Duan and Chao-Hua Deng.
Author contributions: Du ZG conceived and designed the study; led multicenter data collection and integration; performed statistical analysis; drafted and revised the manuscript; Wu YY participated in study design and methodological consultation; assisted in clinical data interpretation and international collaborative validation; critically revised the manuscript for important academic content; Homyy T led data quality control and pathological confirmation of cases; assisted in the development and validation of the predictive model; and participated in manuscript drafting; Zhao WQ, Minsler T, Tekosiv S, Zhang T, Song C, Tui TL, Shi ST, Tan HJ, Jan S, Deng SJ, Qiu LM, Su TX, Teisy S, Zhuang ZX, Xie XJ, Qiu TX, Xiong ZD, Lang TX, Zhen XL, Qin JX, Zheng XB, Teriguezs X, Fie T, and Hasly G participated in multicenter data collection, case screening and local clinical data validation; involved in result discussion and manuscript revision; Duan CK supervised the entire research process; obtained research funding and coordinated multicenter cooperation; determined the study design and finalized manuscript revision; responsible for data integrity and accuracy of analysis; Deng CH supervised the study, provided international expert consultation on pathological classification and predictive model optimization; critically reviewed and approved the final version of the manuscript; Du ZG and Wu YY contributed equally to this manuscript and are co-first authors; Duan CK and Deng CH contributed equally to this manuscript and are co-corresponding authors. All authors have read and approved the final manuscript, confirming that no important content of the study is omitted.
AI contribution statement: ChatGPT was used solely for English translation and language polishing. We confirm that all core content of the manuscript and answering-reviewers, including the research design, data collection, analysis, and interpretation of results, is independently completed by the authors, and AI tools were only used as an auxiliary means for language processing, without involving any substantive research work.
Supported by National Natural Science Foundation of China, No. 82260155 and No. 32573456; 2025 Joint Special Project of Universities in Yunnan Province, No. 202501BA070001-062; Scientific Research Fund Project of Chuxiong Prefecture People’s Hospital, No. 2022YJ14; and Yunnan Provincial Department of Science and Technology Science and Technology Plan Project Contract, No. 202301BA070001-027.
Institutional review board statement: This study was approved by the ethics committee of the People’s Hospital of Chuxiong Yi Autonomous Prefecture (Approval No. 2025-021). The study was conducted in accordance with the Declaration of Helsinki.
Informed consent statement: Written informed consent was obtained from all individual-participants included in the study. Given that this studies multicenter research with a wide research scope covering multiple hospital to fully protect the patient privacy rights in accordance with medical ethics and relevant regulations, our Ethics Review Committee does not recommend the public disclosure of the original informed consent forms of the research subjects.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Due to patient privacy regulations and institutional policies, the datasets are not publicly available. However, anonymized data may be made available upon reasonable request to the corresponding author.
Corresponding author: Chao-Hua Deng, Professor, Department of Urology, The Fourth Affiliated Hospital of Dali University, No. 318 South Lucheng Road, Chuxiong 675000, Yunnan Province, China.
2638522518@qq.com
Received: December 17, 2025
Revised: February 8, 2026
Accepted: May 13, 2026
Published online: June 24, 2026
Processing time: 188 Days and 1.1 Hours
