Protein kinases are potential targets to treat inflammatory bowel disease

doi:10.4292/wjgpt.v5.i4.209

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. Nov 6, 2014; 5(4): 209-217
Published online Nov 6, 2014. doi: 10.4292/wjgpt.v5.i4.209

Table 1 Protein kinases related to inflammatory bowel disease genetics

Kinase	IBD	Ref.
ERK1	CD	[8]
p38	CD and UC	[9]
TYK2	CD and UC	[10]
JAK2	CD and UC	[11]
GCKR	CD	[12]
CDKAL1	CD	[13]
LRRK2	CD	[15]

ERK1: Extracellar signal-regulated Kinase; TYK2: Tyrosine kinase 2; JAK2: Janus kinase 2; GCKR: Glucokinase regulator; CDKAL1: Cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like; LRRK2: Leucine-rich repeat kinase 2; IBD: Inflammatory bowel diseases; UC: Ulcerative colitis; CD: Crohn’s disease.

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Citation: Yang L, Yan Y. Protein kinases are potential targets to treat inflammatory bowel disease. World J Gastrointest Pharmacol Ther 2014; 5(4): 209-217
URL: https://www.wjgnet.com/2150-5349/full/v5/i4/209.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v5.i4.209