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World J Gastrointest Pharmacol Ther. May 6, 2017; 8(2): 114-119
Published online May 6, 2017. doi: 10.4292/wjgpt.v8.i2.114
Inflammatory bowel disease: Efficient remission maintenance is crucial for cost containment
Giovanni C Actis, Rinaldo Pellicano
Giovanni C Actis, Rinaldo Pellicano, the Medical Center Practice Office, 10129 Torino, Italy
Giovanni C Actis, Hepatogastroenterology Division, Ospedale Gradenigo, Corso Regina Margherita, 10153 Torino, Italy
Rinaldo Pellicano, Unit of Gastroenterology, Ospedale Molinette, 10126 Torino, Italy
Author contributions: Actis GC and Pellicano R shared responsibility in study design, manuscript development, and literature search; Pellicano R double-checked the references and formatted the paper.
Conflict-of-interest statement: The authors declare no potential conflicts of interest and no financial support.
Correspondence to: Giovanni C Actis, MD, the Medical Center Practice Office, 10129 Torino, Italy. actis_g@libero.it
Telephone: +39-011-591388 Fax: +39-011-505564
Received: July 27, 2016
Peer-review started: July 29, 2016
First decision: October 20, 2016
Revised: October 28, 2016
Accepted: January 11, 2017
Article in press: January 13, 2017
Published online: May 6, 2017
Processing time: 280 Days and 11.9 Hours
Core Tip

Core tip: Cost-effective maintenance of remission of inflammatory bowel diseases (IBD) is a traditionally unsolved challenge for care-takers and budget supervisors. The newly released (biologic) formulations, though purported to act as disease terminators, have failed to pay back their initial cost. We have faced the issue by reappraising initial simple tenets and found the following: (1) usually, uncomplicated IBD rests in remission by using cheap traditional drugs, provided the indication is correct, and, chiefly, that adherence is tightly maintained. Non compliant IBD patients cost manifold the compliant ones, and are the main cause of budget distortion; and (2) third-party drugs (nonsteroidal anti-inflammatory drugs, e.g., should be avoided. A frozen steady-state is the regime to effectively maintain IBD.