©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. May 6, 2016; 7(2): 179-189
Published online May 6, 2016. doi: 10.4292/wjgpt.v7.i2.179
Published online May 6, 2016. doi: 10.4292/wjgpt.v7.i2.179
Transoral incisionless fundoplication for gastro-esophageal reflux disease: Techniques and outcomes
Pier Alberto Testoni, Giorgia Mazzoleni, Sabrina Gloria Giulia Testoni, Division of Gastroenterology and Gastrointestinal Endoscopy, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, 20132 Milan, Italy
Author contributions: Testoni PA, Mazzoleni G and Testoni SGG equally contributed to this paper with regard to conception and design of the study, literature review, analysis and interpretation of data, drafting the article and making critical revisions related to important intellectual content of the manuscript; Testoni PA contributed to final approval of the version of the article to be published.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Correspondence to: Pier Alberto Testoni, MD, Division of Gastroenterology and Gastrointestinal Endoscopy, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, via Olgettina 58, 20132 Milan, Italy. testoni.pieralberto@hsr.it
Telephone: +39-2-26432756 Fax: +39-2-26433491
Received: October 17, 2015
Peer-review started: October 17, 2015
First decision: November 24, 2015
Revised: December 24, 2015
Accepted: February 23, 2016
Article in press: February 24, 2016
Published online: May 6, 2016
Processing time: 186 Days and 22.2 Hours
Peer-review started: October 17, 2015
First decision: November 24, 2015
Revised: December 24, 2015
Accepted: February 23, 2016
Article in press: February 24, 2016
Published online: May 6, 2016
Processing time: 186 Days and 22.2 Hours
Core Tip
Core tip: Transoral incisionless fundoplication (TIF) has recently emerged as an effective and promising therapeutic option in alternative to medical and surgical therapy for gastro-esophageal reflux disease (GERD). A number of prospective observational studies for TIF using the EsophyX® device have been published but there is still only limited data for TIF with the MUSETM system. This review describes the techniques for TIF with both these devices, and is intended to consolidate the current literature, clarifying better the outcomes of TIF in patients with GERD.