Opioid analgesics for sedation-based gastrointestinal endoscopy

doi:10.4292/wjgpt.v16.i2.102098

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. Jun 5, 2025; 16(2): 102098
Published online Jun 5, 2025. doi: 10.4292/wjgpt.v16.i2.102098

Opioid analgesics for sedation-based gastrointestinal endoscopy

Wei-Lin Yang, Xin-Yu Zhou, Wen-Cai Jiang, Xian-Jie Zhang, Dan Zhou

Wei-Lin Yang, Xin-Yu Zhou, Wen-Cai Jiang, Xian-Jie Zhang, Dan Zhou, Department of Anesthesiology, Deyang People’s Hospital, Deyang 618000, Sichuan Province, China

Wei-Lin Yang, Graduate School, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, Sichuan Province, China

Xin-Yu Zhou, Graduate School, Chengdu Medical College, Chengdu 610500, Sichuan Province, China

Co-corresponding authors: Wei-Lin Yang and Dan Zhou.

Author contributions: Yang WL and Zhou D conceived and designed the study; all authors participated in collecting the literature and drafting the manuscript, revised and approved the final manuscript to be published.

Supported by Wu Jieping Foundation, No. 320.6750.2024-05-55.

Conflict-of-interest statement: The authors declare no conflict of interest.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Wei-Lin Yang, MD, Chief Physician, Department of Anesthesiology, Deyang People’s Hospital, No. 173 North Taishan Road, Deyang 618000, Sichuan Province, China. ywl20100801@126.com

Received: October 8, 2024
Revised: January 13, 2025
Accepted: March 4, 2025
Published online: June 5, 2025
Processing time: 237 Days and 20.5 Hours

Core Tip

Core Tip: Safety, comfort and quality of gastrointestinal endoscopy are the concerns for both patients and doctors. Low-dose synthetic opioids play an important role in this procedure. In China, fentanyl, sufentanil and dezocine are the top three choices. Oliceridine should be paid more attention when performing related studies.