Tandon M, Singh H, Singla N, Jain P, Pandey CK. Tongue thickness in health vs cirrhosis of the liver: Prospective observational study. World J Gastrointest Pharmacol Ther 2020; 11(3): 59-68 [PMID: 32844044 DOI: 10.4292/wjgpt.v11.i3.59]
Corresponding Author of This Article
Manish Tandon, MD, Doctor, Ex Additional Professor Anaesthesia, Department of Anaesthesiology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi 110070, India. manishtandon25@rediffmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World Journal of Gastrointestinal Pharmacology and Therapeutics
ISSN
2150-5349
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Tandon M, Singh H, Singla N, Jain P, Pandey CK. Tongue thickness in health vs cirrhosis of the liver: Prospective observational study. World J Gastrointest Pharmacol Ther 2020; 11(3): 59-68 [PMID: 32844044 DOI: 10.4292/wjgpt.v11.i3.59]
Manish Tandon, Harshita Singh, Chandra Kant Pandey, Formerly at Department of Anesthesia, Institute of Liver and Biliary Sciences, New Delhi 110070, India
Nishant Singla, Formerly at Department of Intervention Radiology, Institute of Liver and Biliary Sciences, New Delhi 110070, India
Priyanka Jain, Formerly at Department of Research, Institute of Liver and Biliary Sciences, New Delhi 110070, India
Author contributions: Tandon M conceived and wrote the manuscript and performed the literature search and review; Sigh H collected and compiled data and reviewed the literature; Singla N collected L3 skeletal muscle index data, trained others on ultrasonography measurements, and supervised ultrasonography measurements; Jain P performed statistical analysis of the data; Pandey CK reviewed the manuscript, and provided intellectual input.
Institutional review board statement: The study was reviewed and approved by the Review Board of the Institution of Liver and Biliary Sciences, New Delhi, India.
Clinical trial registration statement: The study titled “Study of thickness of tongue by ultrasound and its relation with severity of disease in patients with cirrhosis of liver: Prospective Study”, is registered with clinical trials registry of India vide No. CTRI/2017/10/010103.
Informed consent statement: All study participants or their legal guardian provided informed written consent regarding personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: No conflict of interest to declare.
Data sharing statement: There are no additional data available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Corresponding author: Manish Tandon, MD, Doctor, Ex Additional Professor Anaesthesia, Department of Anaesthesiology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi 110070, India. manishtandon25@rediffmail.com
Received: December 29, 2019 Peer-review started: December 29, 2019 First decision: March 27, 2020 Revised: May 17, 2020 Accepted: May 21, 2020 Article in press: May 21, 2020 Published online: August 8, 2020 Processing time: 219 Days and 20.8 Hours
Core Tip
Core tip: Sarcopenia has implications for the management and outcome of patients with cirrhosis of the liver and is therefore included in prognostication. However, the only objective and reproducible measure for sarcopenia using computed tomography (CT) scanning which measures skeletal muscle thickness, is the L3 skeletal muscle index (L3SMI). However, the application of L3SMI is restricted by the need for CT scanning. Compared with CT scan measured L3SMI, tongue thickness can easily be measured in a reproducible manner and accurately with minimal training using ultrasonography and as suggested by this study, is a more sensitive indicator of sarcopenia. Further studies are required to validate these findings and propose tongue thickness as a tool to diagnose sarcopenia.
