Published online Apr 10, 2020. doi: 10.4292/wjgpt.v11.i1.1
Peer-review started: December 31, 2019
First decision: February 19, 2020
Revised: March 15, 2020
Accepted: March 28, 2020
Article in press: March 30, 2020
Published online: April 10, 2020
Processing time: 100 Days and 4.2 Hours
Pancreatic cancer (PC) remains one of the leading causes of cancer-related death in human sowing to missed early and effective diagnosis. The inability to translate research into clinical trials and to target chemotherapy drugs to tumors is a major obstacle in PC treatment. Compared with traditional cancer detection methods, the method combining existing clinical diagnosis and detection systems with nanoscale components using novel nanomaterials shows higher sensitivity and specificity. Nanomaterials can interact with biological systems to efficiently and accurately detect and monitor biological events during diagnosis and treatment. With the advance of experimental and engineering technology, more nanomaterials will begin the transition to clinical trials for their validation. This paper describes a number of nanomaterials used in the diagnosis and treatment of PC.
Core tip: Pancreatic cancer remains one of the leading causes of cancer-related death in humans owing to missed early and effective diagnosis. Nanomaterials can interact with biological systems to efficiently and accurately detect and monitor biological events during diagnosis and treatment in pancreatic cancer.