©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pathophysiol. May 15, 2015; 6(2): 33-42
Published online May 15, 2015. doi: 10.4291/wjgp.v6.i2.33
Published online May 15, 2015. doi: 10.4291/wjgp.v6.i2.33
Current therapy of pediatric Crohn’s disease
Avishay Lahad, Batia Weiss, Pediatric Gastroenterology, Hepatology and Nutrition Unit, Edmond and Lily Safra Children’s Hospital, Sheba Medical Center, Tel Hashomer 52661, Israel
Avishay Lahad, Batia Weiss, Tel-Aviv University, Tel-Aviv 69978, Israel
Author contributions: Lahad A and Weiss B wrote the paper.
Conflict-of-interest: The authors declare that they have no competing interests.
Correspondence to: Avishay Lahad, MD, Pediatric Gastroenterology, Hepatology and Nutrition Unit, Edmond and Lily Safra Children’s Hospital, Sheba Medical Center, Ramat Gan, Tel Hashomer 52661, Israel. avishay.lahad@sheba.health.gov.il
Telephone: +972-3-5305006 Fax: +972-3-5302883
Received: July 24, 2014
Peer-review started: July 24, 2014
First decision: August 15, 2014
Revised: November 3, 2014
Accepted: March 30, 2015
Article in press: April 2, 2015
Published online: May 15, 2015
Processing time: 279 Days and 13.6 Hours
Peer-review started: July 24, 2014
First decision: August 15, 2014
Revised: November 3, 2014
Accepted: March 30, 2015
Article in press: April 2, 2015
Published online: May 15, 2015
Processing time: 279 Days and 13.6 Hours
Core Tip
Core tip: Inflammatory bowel diseases are chronic relapsing diseases of the bowel, with an unknown etiology, rising incidence in the pediatric population, and increasing therapeutic options. The therapeutic goal has changed over the last decade towards accelerated step up or top down therapy with a goal of achieving mucosal healing and perhaps changing the disease course. In this review we discuss these therapeutic approaches.